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Sequentially Shifted Excitation Raman Spectroscopy

November 1, 2014

A method for removing fluorescence-induced backgrounds from Raman spectra using sequentially shifted excitation (SSE) is described. The method uses a temperature-tuned, distributed Bragg reflector diode laser to produce the multiple excitation spectra required to implement the SSE algorithm. Examples applying the SSE method to analysis of motor oils and edible oils are given.

How is Raman spectroscopy improving medicine?

June 24, 2014

Click here to view the complete Wavelength newsletter from June 24, 2014.

Improving Drug Formulation with Raman and IR Spectroscopy

June 24, 2014

The physicochemical properties of drugs are often very diverse and challenging to analyze. Spectroscopy recently spoke with Dr. Lynne Taylor of the Department of Industrial and Physical Pharmacy at Purdue University, and the 2014 Coblentz Society Craver Award winner, about her on-going research using Raman and IR spectroscopy to study drugs and drug excipients - and the interactions of the two.

Key Elements of Confocal Raman Microscopy for High-Resolution Imaging

June 1, 2014

The sensitivity of a high-resolution Raman imaging system is crucial to the quality of the acquired information.

The Use of Portable and Handheld Raman Spectroscopy for Forensic Investigations

June 1, 2014

The Raman technique is gaining widespread acceptance as an investigative tool for forensic applications.

Detection of Melamine and Other Harmful Food Contaminants Using Gold Nanoparticles, Surface-Enhanced Raman Scattering, and Raster Orbital Scanning

June 1, 2014

Melamine is a dangerous substance when it is used to increase the apparent protein content of food. In this article, the use of novel gold nanoparticles for surface-enhanced Raman spectroscopy (SERS) measurements with raster orbital scanning sampling is described for the detection of melamine and other food contaminants.

Raman Microscopy for Detecting Counterfeit Drugs — A Study of the Tablets Versus the Packaging

June 1, 2014

Results of tablet matching measurements and characterization of packaging are presented.

High-Speed TERS Imaging: The Latest Achievements in nano-Raman Spectroscopy

June 1, 2014

This article presents developments in tip-enhanced Raman spectroscopy (TERS) that make possible nanoscale imaging of chemical and physical properties of graphene and other carbon species: Innovative integration of technologies brings high-throughput optics and high-resolution scanning for high-speed imaging without interferences between the techniques.

Overview of High-Efficiency Transmission Gratings for Molecular Spectroscopy

April 1, 2014

This article provides a basic overview of the capabilities of transmission gratings optimized for molecular spectroscopy.

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Emerging Trends in Pharmaceutical Analysis
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