Diagnosing Disease with Raman Spectroscopy
Vibrational spectroscopic techniques such as Raman spectroscopy have taken on increasingly important roles in point-of-care testing, spectral histopathology, and rapid in vivo diagnostics. Nick Stone is a Professor of Biomedical Imaging and Biosensing at the University of Exeter, and he and his group use Raman spectroscopy for measuring changes in the molecular constituents of cells and tissues as disease develops. He recently spoke to us about this work.
Using Thermostable Raman Interaction Profiling (TRIP) For Protein Binding Screening
March 1st 2024Narangerel Altangerel, Zhenhuan Yi, and Marlan Scully of Texas A&M University recently used TRIP to analyze eight protein–ligand systems. Spectroscopy recently spoke to these three researchers about their findings and what the implications are for high-throughput drug screening.
Synthesizing Synthetic Oligonucleotides: An Interview with the CEO of Oligo Factory
February 6th 2024LCGC and Spectroscopy Editor Patrick Lavery spoke with Oligo Factory CEO Chris Boggess about the company’s recently attained compliance with Good Manufacturing Practice (GMP) International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) Expert Working Group (Q7) guidance and its distinction from Research Use Only (RUO) and International Organization for Standardization (ISO) 13485 designations.
Reviewing the Impact of Raman Spectroscopy on Crop Quality Assessment: An Interview with Miri Park
February 1st 2024Miri Park of the Fraunhofer Institute for Environmental, Safety, and Energy Technologies is examining how Raman spectroscopy could aid non-destructive sensing in agricultural science. Recently, Park sat down with Spectroscopy to discuss micro-Raman spectroscopy's role in assessing crop quality, particularly secondary metabolites, across different contexts (in vitro, in vivo, and in situ), while suggesting future research for broader application possibilities.
