Mass Spectrometry

Jul 01, 2014
Special Issues
Canola largely contains unsaturated fatty acids, thus rendering it clear in most cases after extraction and refining.
Jul 01, 2014
Special Issues
Direct sample analysis coupled to high-resolution time-of-flight mass spectrometry (TOF-MS) may be effective at analyzing synthetic cathinones, especially for qualitative analysis, because it does not require potentially tedious sample preparation.
Jul 01, 2014
Special Issues
Military jet fuel (JP-8) is very similar to commercial jet fuel (Jet A) except for the presence of three additives, fuel system icing inhibitor, corrosion inhibitor–lubricity improver (CI-LI), and antistatic additive, which are added to improve characteristics of JP-8.
May 01, 2014
Special Issues
In this article, we examine how tandem and tandem hybrid mass spectrometry has opened up new frontiers already. We go further and examine how lesser-known experiments are breaking new ground, with alternative fragmentation techniques, as well as the addition of extra levels of orthogonality by parallel separations techniques.
May 01, 2014
Special Issues
The identification of nontargeted species in environmental and commercial samples by mass spectrometry can be very difficult. In this article, authors from Eastman Chemical Company describe their systematic approach for the identification of nontargeted species using nominal and accurate mass data, searching both mass spectral and "spectra-less" databases.
May 01, 2014
Special Issues
Ionization of small, large, volatile, and nonvolatile compounds with charge states nearly identical to electrospray ionization are produced from a solid matrix or solution with high sensitivity utilizing the vacuum inherent with any mass spectrometer. With the proper matrix, analytes can be analyzed from ambient conditions or by direct introduction into vacuum.
May 01, 2014
Special Issues
Native mass spectrometry, the method by which noncovalent protein complexes are retained in the gas phase for intact mass analysis, is gaining interest as a method for intact protein characterization. The development of a modified orbital ion trap platform for high-resolution analyses has expanded the role of native mass spectrometry to address the challenges of intact protein characterization.
Apr 15, 2014
Wavelength
By Spectroscopy Editors
Mass spectrometry is a powerful analytical tool. Yet researchers and instrument makers continue to push the limits of its resolving power. One such researcher is David E. Clemmer, the Robert & Marjorie Mann Chair and Distinguished Professor of Chemistry at Indiana University in Bloomington, Indiana and the 2014 Anachem Award winner. Clemmer's group has done extensive research to develop and improve ion trapping techniques and ion mobility spectrometry-mass spectrometry (IMS-MS) instruments to analyze biomolecular mixtures and structures.
Mar 01, 2014
Special Issues
Translational proteomics has not been as successful as originally anticipated. Because mass spectrometry (MS) can separate proteins at the sequence level, it provides the selectivity needed for this application; however, traditional challenges still exist, including time-to-result, throughput, and sample-size requirements.
Mar 01, 2014
Special Issues
Despite the advantages of soft ionization ion-source technologies for improving confidence in the identification of a range of challenging analytes, soft ionization remains a niche technique for gas chromatography–mass spectrometry (GC–MS).
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