Spectroscopy April 2017

April 2017 | Volume 32, Issue 4
Focus On Quality
Data integrity requires a multilayered approach that runs throughout a regulated organization. Here we discuss the laboratory level, and discuss the impact of the data governance scheme as it cascades down to the processes and systems at the bench. The main focus here is on data ownership and data stewards.
IR Spectral Interpretation Workshop
Our survey of the spectroscopy of the C–O bond continues. Here, we complete our discussion of alcohols and discuss how to distinguish pure alcohols, alcohol–water mixtures, and pure water from each other.
Peer-Reviewed Articles
With superior detection sensitivity, chemical specificity, and spatial–temporal resolution, pump–probe microscopy is an emerging tool for functional imaging of nonfluorescent chromophores and nanomaterials. This article reviews the basic principles and discusses applications such as imaging semiconductor materials and heme-containing proteins.
Transmission Raman spectroscopy overcomes subsampling limitations of conventional Raman spectroscopy and enables rapid noninvasive volumetric analysis of intact pharmaceutical tablets and capsules in a quantitative manner, making it suitable for process and quality control applications.
Interviews
By Spectroscopy Editors
Duncan Graham of the University of Strathclyde is pushing the limits of what can be achieved using functionalized nanoparticles and SERS, in applications such as cholera detection, lipid profiling in cancer cells, and assessing the efficacy of anti-cancer drugs.
By Spectroscopy Editors
Jennifer S. Brodbelt of the University of Texas at Austin discusses the development and application of photodissociation mass spectrometry for studying biological molecules such as peptides, proteins, nucleic acids, oligosaccharides, and lipids.
Market Profile
By Spectroscopy Editors
Although weakness in the metals and mining industry has challenged the market for spectroscopy instruments in 2016, the demand for environmental and food testing has been robust, forging growth for key technologies such as ICP and ICP-MS.
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