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Mass Spectrometry

Application of Ambient Sampling Portable Mass Spectrometry Toward On-Site Screening of Clandestine Drug Operations

October 1, 2014

Worldwide trends in illicit drug use and production have shifted toward an increase in synthetic analogues and the emergence of new variations in their manufacture.

GC–MS Analysis of an Herbal Medicinal Remedy to Identify Potential Toxic Compounds

October 1, 2014

In most countries, herbal medicinal products (HMPs) are introduced into the market without proper scientific evaluation or enforced safety and toxicological studies.

Unraveling the Links Between Diet and Human Health Using LC–MS-MS

October 1, 2014

We recently spoke to Gary Duncan and Wendy Russell of the Rowett Institute of Nutrition & Health in Aberdeen, Scotland, about the significance of phytochemical bioavailability to human health and the important role of liquid chromatography linked to tandem mass spectrometry (LC–MS-MS) in their research.

Simultaneous Determination of Methylxanthines and Cotinine in Human Plasma by Solid-Phase Extraction Followed by LC–MS-MS

October 1, 2014

A multiresidue method has been developed and validated for the analysis of methylxanthines (caffeine and its metabolites) and cotinine in human plasma.

Large-Scale Targeted Protein Quantification Using Wide Selected-Ion Monitoring Data-Independent Acquisition

October 1, 2014

This article describes the development of a new data-independent acquisition (DIA) workflow for protein quantification that uses a mass spectrometer that combines three types of mass analyzers to achieve lower limits of detection (LOD), higher sensitivity, more accurate quantitative results, wider dynamic range, and better reproducibility than existing high-resolution accurate-mass (HRAM) tandem mass spectrometry (MS-MS) DIA workflows.

Current Trends in Mass Spectrometry: July 2014

July 29, 2014

Click here to view the complete Wavelength newsletter from July 29, 2014.

A New Mass Spectrometry Method for Analyzing Complex Samples

July 15, 2014

This interview with Steven J. Ray, an Associate Scientist in the Department of Chemistry at Indiana University in Bloomington, Indiana, discusses his work with a new form of mass spectrometry (MS) for analyzing complex samples.

Analyzing Synthetic Cathinones Using Direct Sample Analysis Time-of-Flight Mass Spectrometry

July 1, 2014

Direct sample analysis coupled to high-resolution time-of-flight mass spectrometry (TOF-MS) may be effective at analyzing synthetic cathinones, especially for qualitative analysis, because it does not require potentially tedious sample preparation.

LC–MS Identification of Wax Esters in Cloudy Canola Oil

July 1, 2014

Canola largely contains unsaturated fatty acids, thus rendering it clear in most cases after extraction and refining.

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