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Mass Spectrometry

Detecting Ions in Mass Spectrometers with the Faraday Cup

November 1, 2011

The Faraday cup has been associated with mass spectrometry since the first instruments were assembled and continues to be used today. Here's how it works.

On- and Off-Line Coupling of Separation Techniques to Ambient Ionization Mass Spectrometry

October 1, 2011

A review highlighting the combination, or potential combination, of various separation methods with ambient ionization mass spectrometry

Creating a High-Throughput LC–MS-MS System Using Common Components

October 1, 2011

How to create a liquid chromatography–tandem mass spectrometry (LC–MS-MS) system using mass spectrometers, a high performance liquid chromatography (HPLC) binary pump system, and an autosampler

Probing Aqueous Surfaces by TOF-SIMS

October 1, 2011

A breakthrough using a microfluidic interface to conduct sensitive time-of-flight secondary ion mass spectrometry (TOF-SIMS) analysis and study liquid surfaces in situ under vacuum conditions is described here.

Call for Papers

October 1, 2011

Spectroscopy invites researchers to submit their work for publication.

Analytical Strategies in the Development of Generic Drug Products: The Role of Chromatography and Mass Spectrometry

October 1, 2011

A discussion of active pharmaceutical ingredient (API) selection, drug product development, and mass spectrometry instrumentation

Matrix-Assisted Laser Desorption-Ionization Imaging Mass Spectrometry for Direct Tissue Analysis

October 1, 2011

A summary of the most recent advances in sample preparation, instrumentation, and data-processing techniques for MALDI-IMS

Consequences of Finite Ion Lifetimes in Mass Spectrometry

September 1, 2011

Consequences of Finite Ion Lifetimes in Mass Spectrometry As we construct more-complex instruments that process packets of ions in time and space, the issue of ion lifetimes is becoming more important.

High-Definition Screening for Boar Taint in Fatback Samples Using GC–MS

July 1, 2011

High-definition screening by gas chromatography–mass spectrometry (GC–MS) is shown to be a viable option for the reliable identification of odorous compounds in pork.

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