Special Issues-05-01-2014

Special Issues

High-Resolution Native Mass Spectrometry Opens the Door for Detailed Analyses of Intact Protein Complexes

May 01, 2014

Articles

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Native mass spectrometry, the method by which noncovalent protein complexes are retained in the gas phase for intact mass analysis, is gaining interest as a method for intact protein characterization. The development of a modified orbital ion trap platform for high-resolution analyses has expanded the role of native mass spectrometry to address the challenges of intact protein characterization.

A Convenient Alternative to MALDI and ESI

May 01, 2014

Articles

12

2

Ionization of small, large, volatile, and nonvolatile compounds with charge states nearly identical to electrospray ionization are produced from a solid matrix or solution with high sensitivity utilizing the vacuum inherent with any mass spectrometer. With the proper matrix, analytes can be analyzed from ambient conditions or by direct introduction into vacuum.

Identifying "Known Unknowns" in Commercial Products by Mass Spectrometry

May 01, 2014

Articles

12

2

The identification of nontargeted species in environmental and commercial samples by mass spectrometry can be very difficult. In this article, authors from Eastman Chemical Company describe their systematic approach for the identification of nontargeted species using nominal and accurate mass data, searching both mass spectral and "spectra-less" databases.

The Fundamental Shift to Tandem Mass Spectrometry

May 01, 2014

Articles

12

2

In this article, we examine how tandem and tandem hybrid mass spectrometry has opened up new frontiers already. We go further and examine how lesser-known experiments are breaking new ground, with alternative fragmentation techniques, as well as the addition of extra levels of orthogonality by parallel separations techniques.

Vol 12 No 2 Current Trends in Mass Spectrometry May 2014 Issue PDF

May 01, 2014

Issue PDF

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Click the title above to open the May 2014 issue of Current Trends in Mass Spectrometry, Volume 12, Number 2, in an interactive PDF format.