Symposium: Atomic Tools as Solutions to Molecular Problems
This Monday morning session will be presided over by Jacob T. Shelley of Kent State University.
Session 290, Room 255, 8:30 a.m.
This Monday morning session will be presided over by Jacob T. Shelley of Kent State University.
The session will begin with a presentation by Gary M. Hieftje of Indiana University titled “Plasma Spectrometry - Not Just for Atoms Anymore.” Hieftje will focus on plasma sources that are capable of molecular characterization and speciation in applications such as spots in thin-layer chromatography or 2D gel electrophoresis.
The next presentation in the session is titled “Laser Ablation Molecular Isotopic Spectrometry (LAMIS) – Direct Solid-Sample Isotopic Analysis Through All-Optical Means” and will be delivered by George Chan of Lawrence Berkeley National Laboratory. Chan will present an overview of the theoretical principles of LAMIS and will discuss the analytical figures of merit and challenges of the technique.
Gunnar Schwarz of ETH Zurich will present the next talk, titled “Single-Cell-Based Tissue Analysis by Isotopically Tagged Antibodies Using Laser Ablation-cy TOF.” This presentation will discuss various in-house built laser ablation systems and ablation cell geometries for fast screening of tissue and how the wavelength of the laser for tissues is less crucial than for geological samples.
Following a 15-min recess, Gerardo Gamez of Texas Tech University will present a talk titled “‘Say Cheese’: Getting the Molecular Picture with Plasmas.” Gamez will discuss the use of glow-discharge optical emission spectroscopy for analyzing biological thin sections and imaging methods for molecules used for therapeutic compounds, contrasting agents, and toxicology studies.
The final presentation in the session is scheduled to be given by Jacob T. Shelley and is titled “The Atomic Side of Molecular Mass Spectrometry.” This presentation will discuss a novel plasma source for obtaining molecular, structural, and atomic information when it is coupled with mass spectrometry. Shelley will describe the source’s design, operation, and representative applications.
Getting accurate IR spectra on monolayer of molecules
April 18th 2024Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.
