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Articles

Single-cell ICP-MS was used to study the uptake and apoptotic status of nanoplatinum (IV) treated cells, specifically selenized yeast, and the question of using commercialized reference material to validate single cell ICP-MS analysis is addressed.

Toward Normalization of Quantitative Single Cell ICP-MS Experiments

We interviewed an AI program (ChatGPT) for Spectroscopy asking questions about AI and its role in various applications for vibrational and atomic spectroscopy, including data analysis. 

An Interview with AI About Its Potential Role in Vibrational and Atomic Spectroscopy

Gary McGeorge, Scientific Director at Bristol-Myers Squibb, spoke to us of the benefits and challenges associated with establishment of consistent resolutions while facilitating the steps associated with the implementation of process analytical technology (PAT).

Standardizing Solutions to Enabling Platforming of Process Analytical Technology (PAT) Deployments

ICP-MS was used to measure 46 different elements in 37 Azobé (Lophira alata) trees at two forest sites in Cameroon to determine the multi-elemental composition of trees in an effort to combat the illegal trade of timber.

Clay and Soil Organic Matter Drive Wood Multi-Elemental Composition of a Tropical Tree Species: Implications for Timber Tracing

Although milk is considered among the most complete and nutrition-rich natural foods, the concentration of vitamins and minerals in milk can vary depending on a variety of circumstances. Stelios Couris of the University of Patras and the Foundation for Research and Technology-Hellas (Patras, Greece) has been studying the inorganic elemental composition of a variety of milk samples using LIBS and spoke to Spectroscopy about this research.

Analysis of the Inorganic Content of Milk via Laser Induced Breakdown Spectroscopy

Combining multiplex coherent anti-Stokes Raman scattering (MCARS) microscopy with automated data processing enables a simple and more accessible method for label-free bioimaging.

Coherent Anti-Stokes Raman Scattering Cell Imaging and Segmentation with Unsupervised Data Analysis

Zac Schultz, a professor at the Ohio State University, and his graduate student Hannah Schorr, are working on the use of surface-enhanced Raman spectroscopy (SERS) for the differentiation of glycans. Schultz and Schorr spoke to Spectroscopy about this work. 

Differentiating Glycans by Surface-Enhanced Raman Spectroscopy

Recently, at the 2022 SciX conference in Covington, Kentucky, Beatriz Fernandez, who is an Associate Professor at the University of Oviedo in Spain, presented, as part of the Technical Program, a discussion regarding the determination of proteins in single cells by ICP-MS using metal nanoclusters as labels of specific recognition reactions. Fernandez spoke to Spectroscopy about her presentation. 

Determination of Proteins in Single Cells by Inductively Coupled Plasma–Mass Spectrometry Using Metal Nanoclusters as Labels of Specific-Recognition Reactions

Harishchandra Singh, Graham King and associates have employed high energy synchrotron X-ray diffraction (HE-SXRD) experiments and an analytical model in order to predict the yield strength of cerium-modified super duplex stainless steel (SDSS) subjected to various cold- and cryo-deformation. Spectroscopy recently had the opportunity to discuss the experiments and the findings with Singh and King.

Quantitative Prediction of Yield Strength of Highly Alloyed Complex Steel Using High Energy Synchrotron X-Ray Diffractometry

In the treatment of tuberculosis (TB), a contagious disease that causes 1.5 million deaths per year globally, early diagnosis is critical in order to control its spread. Unfortunately, standard tuberculosis diagnostic tests, such as sputum culture, can take days to weeks to yield results. In a recent paper, Ubaid Ullah of the Syed Babar Ali School of Science and Engineering in Pakistan and his colleagues demonstrate a quick, portable, easy-to-use, and non-invasive optical sensor based on sputum samples for tuberculosis detection using Raman spectroscopy to detect TB in a patient’s sputum supernatant. Ullah spoke to Spectroscopy about this sensor and its development.

Spectroscopy Interviews