Inductively coupled plasma–mass spectrometry (ICP-MS) has become a successful approach for fast, multielemental analysis, and analysts are applying it to a wide range of analyses, including geochemical, environmental, forensic, and medical studies. Uwe Karst is a Professor and Chair of the Analytical Chemistry Department at the University of Münster in Germany, and he and his group use ICP-MS for applications such as analyzing magnetic resonance imaging (MRI) contrast agents in river water, speciation analysis in a study of a disease related to renal failure, and examining the distribution of a labeling compound in mouse tumor cells and macrophages. He recently spoke to us about this work.
By Spectroscopy Editors
Although near-infrared (NIR) spectroscopy is not a particularly sensitive technique, it can be implemented with little or no sample preparation and thus is well suited to applications such as process monitoring, materials science, and medical uses. We asked a panel of experts to comment on important current applications of NIR, as well as emerging new areas of application and the challenges involved in those newer applications.
Although handheld FT-IR spectrometers now make it possible to carry out field-based FT-IR analysis of soils at a crime scene, reliable and tested protocols are not yet available for such work. Here, we discuss sampling options and describe tests of a methodology that is being eveloped for in situ FT-IR analysis of soil samples.
Quality control of silicones used in medicinal implants is challenging, and traditional methods waste a lot of raw material. In this study, NIR spectroscopy has been used to replace the traditional rheometric measurements, with excellent results. The NIR method enables improved quality control and a more economical process.
Infrared multiple angle incidence resolution spectroscopy (IR MAIRS) provides a powerful new tool to determine the molecular structure and orientation in a thin film on an IR-transparent substrate. The MAIRS technique replaces a tedious, and sometimes impossible, combination of sample preparation and analysis of identical films on both transparent and reflective substrates.
Macro attenuated total reflection FT-IR spectroscopic imaging is a powerful and underutilized tool. This article presents an overview of approaches and opportunities for using this method to study dynamic processes such as diffusion, sorption, crystallization, and dissolution.
Evaluation of the discrimination power of Raman spectroscopy in decreasing turnaround time in clinical diagnosis, when analyzing microcolonies from nine bacterial and one yeast species directly on solid culture medium after a shortened incubation time.
Statistical and morphological analysis of particles on a filter has been complemented by chemical analysis based on Raman spectroscopy using the ParticleFinder tool, allowing further insight into the particle composition and its origin within a production line.
The application note explains how the Raman Spectroscopy can be helpful in the analysis of cathodes and anodes in Li-ion batteries.
By Spectroscopy Editors
Imaging techniques using vibrational spectroscopy, mass spectrometry (MS), and atomic force microscopy have all been advancing and gaining momentum in recent years. There is great potential power in these imaging techniques, particularly in the biomedical field. Thomas Bocklitz of at the Friedrich-Schiller-University Jena is working to better harness the power of these techniques by combining them.
By Spectroscopy Editors
Recent reports of the successful use of Raman spectroscopy for important biomedical applications are quite exciting. These applications include imaging for disease diagnosis, including significant improvements for endoscopic probes, and identification of microorganisms. But is it truly practical and feasible to implement Raman technologies in a clinical environment?
This article provides a basic overview of the capabilities of transmission gratings optimized for molecular spectroscopy.
Simulated leaf spectral data were generated to analyze scattering impact and then compared to experimental data to validate the conclusions of the simulation.
The wavelet packet transform (WPT) combined with the modified uninformative variable elimination (MUVE) method (WPT–MUVE) is proposed to select variables for multivariate calibration of spectral data.
The development of a method for the simultaneous determination of glycine, triglycine and fructose using UV–vis and evaporative light-scattering detection (ELSD) is described. This was necessary as part of a research project dealing with the recovery of functional peptides from aqueous streams on an industrial scale using adsorption or related technologies. Fructose is barely detectable by UV–vis as it lacks detectable functionalities, while glycine and triglycine are both UV–vis sensitive. An NH2 phase was chosen as a column and separation was obtained within seven minutes on a 250 X 4.6 mm column. Limits of detection are approximately 40 mg fructose/L, 4 mg glycine/L and 0.05 mg triglycine/L. Calibration functions are linear in a range of 40–1400 mg/L for fructose, 5–200 mg/L for glycine and 0.5–70 mg/L for triglycine.
Raman technologies offer promise for important areas of agricultural and environmental management, such as food safety, air emissions, water monitoring, and GMO labeling.
A new method was developed for BHA determination in edible and essential oils by SERS Raman microscopy, without the need for any sample handling or pretreatment.
Zinc telluride films doped with gadolinium (ZnTe:Gd)—made by laser ablation and deposition—have been characterized by X-ray photoelectron spectroscopy (XPS) to determine the molecular species of the elements in the material and their presence as intentionally formed contaminants.
An interlaboratory comparison study for the measurement of arsenic species in rice,kelp, and apple juice was carried out.
The analysis of seals, mostly via the ink types, can provide evidence to authenticate the related documents and can play a key role in legal cases. In the present study, a method to discriminate red seal inks using Raman microscopy and Fourier transform infrared (FT-IR) spectroscopy was developed.
The Society for Applied Spectroscopy (SAS) presented the SAS undergraduate student research excellence, student poster awards, and student travel grants, on Sunday, September 27, at SciX 2015, at the opening reception and student poster session.
Nipro Corporation (Osaka, Japan) has signed a definitive agreement to acquire Infraredx, Inc. (Burlington, Massachusetts).
The 2015 SciX Conference, presented by FACSS, is bringing together top scientists to address the complex issues of analytical chemistry in the developing world.
By Laura Bush
In honor of Spectroscopy’s celebration of 30 years covering the latest developments in materials analysis, we asked experts to assess the current state of the art of six key spectroscopic techniques. Here, the experts weigh in on what they considered the most important advance in inductively coupled plasma–mass spectrometry (ICP-MS) in the last 5–10 years.
By Laura Bush
In honor of Spectroscopy's celebration of 30 years covering the latest developments in materials analysis, we asked a panel of experts to assess the current state of the art of inductively coupled plasma–mass spectrometry (ICP-MS) and to try to predict how the technology will develop in the future.
Rare earth elements (REEs) have become indispensable in many electronic, optical, magnetic, and catalytic applications because of their specific properties such as magnetism and phosphorescence, as well as their ability to both donate and accept electrons.
This article compares several performance criteria such as full width at half maximum, background equivalent concentrations, limits of detection, purge requirements, and results for some substances for the "traditional" As lines at 188.979, 193.696, and 197.197 nm for the "new" line at 228.812 nm.
A novel approach to handling samples with very high and variable levels of sample matrix is to use aerosol dilution, whereby the amount of sample aerosol that reaches the plasma is reduced by dilution with an additional argon gas stream.
A multiresidue method has been developed and validated for the analysis of methylxanthines (caffeine and its metabolites) and cotinine in human plasma.
This article describes the development of a new data-independent acquisition (DIA) workflow for protein quantification that uses a mass spectrometer that combines three types of mass analyzers to achieve lower limits of detection (LOD), higher sensitivity, more accurate quantitative results, wider dynamic range, and better reproducibility than existing high-resolution accurate-mass (HRAM) tandem mass spectrometry (MS-MS) DIA workflows.
In most countries, herbal medicinal products (HMPs) are introduced into the market without proper scientific evaluation or enforced safety and toxicological studies.
Worldwide trends in illicit drug use and production have shifted toward an increase in synthetic analogues and the emergence of new variations in their manufacture.
By Spectroscopy Editors
We recently spoke to Gary Duncan and Wendy Russell of the Rowett Institute of Nutrition & Health in Aberdeen, Scotland, about the significance of phytochemical bioavailability to human health and the important role of liquid chromatography linked to tandem mass spectrometry (LC–MS-MS) in their research.