April 26th 2024
A recent study uses Fourier transform infrared (FT-IR) spectroscopy to study biochemical changes associated with child obesity.
Resonant Surface-Enhanced Infrared Spectroscopy (Resonant SEIRA) Using Metal Nanoantennas
August 1st 2021Resonant SEIRA overcomes the limitations of traditional Fourier transform infrared (FT-IR) spectroscopy for minute sample sizes of relatively low absorptivity. Frank Neubrech of Heidelberg University is exploring resonant SEIRA in applications such as monitoring dynamic processes and hyperspectral infrared chemical imaging.
Fingerprinting of Mineral Medicine Natrii Sulfas by Fourier Transform Infrared Spectroscopy
June 1st 2021We show how FT-IR may be used for quality control analysis of natrii sulfas, a transparent crystalline material used in natural medicine that primarily contains sodium sulfate decahydrate, crystallized from sulfate minerals.
The Grand Review I: Why Do Different Functional Groups Have Different Peak Positions?
November 1st 2020Articles in this column have addressed five main areas: theory, functional groups containing the C-H bond, those containing the C-O bond, those with the C=O bond, and those with organic nitrogen compounds. Here, we review the concepts.
Insights Toward Standardization of the Analysis of Microplastics by Infrared Microscopy
August 1st 2020Here we conduct an evaluation of significant operational parameters of IR microscopy for accurately determining the size of microplastics, with the overarching goal of outlining performance parameters that will help in the standardization of microplastics analysis.
Organic Nitrogen Compounds VIII: Imides
March 1st 2020Here, we continue our examination of the infrared (IR) spectra of organic nitrogen compounds with imides, which are a common chemical intermediate. IR can be used not only to identify imides, but also to distinguish between straight chain and cyclic imides. We explain how.
Analysis of FDA Infrared 483 Citations: Have You a Data Integrity Problem?
September 1st 2019Analysis of FDA Form 483 observations and warning letters for infrared spectrometers reveals a range of data integrity problems and a lack of laboratory procedures for the technique. Is your laboratory in the same situation?
Advancing Biomedical Research with New Infrared and Raman Microscopy Techniques
June 10th 2019Significant progress is being made to harness the power of spectroscopy technique for medical research. An ongoing challenge, and area of development, in this effort, is to “see” more and more detail about biological activity, even within individual cells. Ji-Xin Cheng, a professor of biomedical engineering at Boston University, is advancing such work, by developing techniques like midinfrared photothermal (MIP) imaging and Raman spectromicroscopy. Cheng is the 2019 winner of the Ellis R. Lippincott Award, which is awarded annually by the Optical Society, the Coblentz Society, and the Society for Applied Spectroscopy, to an individual who has made significant contributions to the field of vibrational spectroscopy. Here, Cheng speaks to us about those techniques.
The Use of Portable Near-Infrared Spectroscopy for Authenticating Cardiovascular Medicines
May 1st 2019Portable NIR spectroscopy is demonstrated as a rapid and mobile analysis method for authenticating cardiovascular medicines in critical situations, and to indicate whether formulations are counterfeit or substandard.
The C=O Bond, Part VII: Aromatic Esters, Organic Carbonates, and More of the Rule of Three
September 1st 2018Aromatic esters follow the ester Rule of Three, but each of these three peak positions is different for saturated and aromatic esters, which makes them easy to distinguish. Organic carbonates are structurally similar to esters and follow their own Rule of Three.