|Articles|March 1, 2009

Spectroscopy

  • Spectroscopy-03-01-2009
  • Volume 24
  • Issue 3

Market Profile: Lifetime Fluorescence

Lifetime fluorescence is a subset of fluorescence spectroscopy in which the time between excitation and relaxation is measured, rather than just the intensity of the emitted energy. The technique is used primarily in biological applications, but has a number of other uses as well. Lifetime fluorescence is a well-established niche market.

Lifetime fluorescence is a subset of fluorescence spectroscopy in which the time between excitation and relaxation is measured, rather than just the intensity of the emitted energy. The technique is used primarily in biological applications, but has a number of other uses as well. Lifetime fluorescence is a well-established niche market.

Lifetime fluorescence demand by industry - 2008.

Lifetime fluorescence typically measures the time it takes for molecules to fluoresce after being excited by a light source. Frequency domain lifetime fluorescence compares the modulation and phase-shift of the emitted energy relative to the excitation energy instead. An increasingly popular technique within the lifetime fluorescence market is FLIM, which stands for "Fluorescence Lifetime Imaging," and is very useful for examining biological tissues.

Lifetime fluorescence is by far most popular in biological analyses, which accounts for more than half of demand when considering academia, government, and hospital & clinical applications. There is limited application in areas such as electronics for developing LEDs, characterizing polymers in the plastics industry, and identification and characterization of crude oil in the environmental and oil & gas industries.

The total market for lifetime fluorescence was about $18 million in 2008. Despite the global recession, demand is not likely to contract drastically due to its connection to the healthcare, academic, and government areas. Longer-term annual growth is likely to be in the low single digits.

The foregoing data were based on SDi's market analysis and perspectives report entitled Global Assessment Report, 10th Edition: The Laboratory Life Science and Analytical Instrument Industry, September 2008. For more information, contact Stuart Press, Vice President – Strategic Analysis, Strategic Directions International, Inc., 6242 Westchester Parkway, Suite 100, Los Angeles, CA 90045, (310) 641-4982, fax: (310) 641-8851, www.strategic-directions.com.


Related to this article

Brandon E. Boor is the Dr. Margery E. Hoffman Associate Professor in the Lyles School of Civil and Construction Engineering at Purdue University. | Photo Credit: © Brandon Boor.
In the second part of our interview with Brandon Boor of Purdue University, he discusses how his team controls experimental variables during cleaning experiments in order to obtain interpretable data.
Scientist With Portable Spectrometer in Natural Field Setting ©  By Tika -chronicles-stock.adobe.com
The bulky bench-top NIR spectrometer is quietly being dismantled and rebuilt as a wafer-scale photonic chip, a self-calibrating algorithm, and a sensor small enough to ride in a shirt pocket. What once demanded a grating, a moving mirror, and a climate-controlled lab now fits inside a handheld module, a bioreactor probe, or a drone payload, and it increasingly figures out what it is looking at on its own.
Sizing Up the Nanoscale: Measuring Nanocluster Aerosol in Indoor Air
In the first part of a multi-part Q&A, Brandon Boor, the Dr. Margery E. Hoffman Associate Professor in the Lyles School of Civil and Construction Engineering at Purdue University, describes the instrumentation and methodology behind measuring nanoparticle size distributions at the nanocluster scale (1–3 nm) and outlines the technical challenges of acquiring reliable, real-time data at these dimensions.
Human body wireframe on glowing platform undergoing futuristic body scan. © sergray(noAIelemens) -chronicles-stock.adobe.com
Jurgen Popp, Thomas Mayerhofer, and colleagues at Leibniz IPHT and Friedrich Schiller University Jena introduce the Personalized Optical Digital Twin (PODT), a Photonics21 contribution to Europe's Virtual Human Twin ecosystem that connects molecular photonics—Raman blood analysis, coherent Raman tissue imaging, and multimodal endomicroscopy—with longitudinal physiology and clinical data. Drawing on the published multicenter INTELLIGENCE trials, the authors argue that technical feasibility and clinical utility must be evaluated separately as the field moves toward Europe's FP10 research agenda.