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The Growing Process Analytical Technology Market
0:45
The Growing Process Analytical Technology Market
5 hours ago
by
Janam Pandya
The Challenges Forensic Scientists Face Today
1:14
The Challenges Forensic Scientists Face Today
a day ago
by
Tom Spudich
The Interdisciplinary Nature of Science
2:38
The Interdisciplinary Nature of Science
2 days ago
by
Janam Pandya
Best of the Week: Biscayne Bay, Analyzing Blended Fibers
0:29
Best of the Week: Biscayne Bay, Analyzing Blended Fibers
5 days ago
by
Will Wetzel
The Role of Spectroscopy in Studying Caves
0:50
The Role of Spectroscopy in Studying Caves
7 days ago
by
Will Wetzel
The Value of O-PTIR Spectroscopy in Analyzing Microplastics
0:54
The Value of O-PTIR Spectroscopy in Analyzing Microplastics
8 days ago
by
Will Wetzel
The Importance of Writing and Communication Skills in Spectroscopy
1:02
The Importance of Writing and Communication Skills in Spectroscopy
9 days ago
by
Mary Kate Donais
Best of the Week: Upcoming Spectroscopy Conferences, University Archaeometry Programs
0:37
Best of the Week: Upcoming Spectroscopy Conferences, University Archaeometry Programs
12 days ago
The Oil and Gas Value Chain: Is it Complex?
0:57
The Oil and Gas Value Chain: Is it Complex?
14 days ago
by
Janam Pandya
Which Applications Are X-ray Techniques Finding Success In?
1:15
Which Applications Are X-ray Techniques Finding Success In?
15 days ago
by
Will Wetzel

When Political Appointees Outrank Peer Review

How a New Office of Management and Budget Rule Could Reshape Spectroscopy and Scientific Research Funding

When Political Appointees Outrank Peer Review

Spectroscopy Top 10 Articles of the Month

An Inside Look at the Best of June 2026

Spectroscopy Top 10 Articles of the Month

Back to Basics

Analyzing the State of Forensic Science in 2026

Back to Basics

What Spectroscopic Techniques Are Used in Modern Oil Refining?

An Inside Look

What Spectroscopic Techniques Are Used in Modern Oil Refining?

What Are Some of the Keynote Events Set to Take Place at the ACS Fall 2026 Meeting?

An Inside Look

What Are Some of the Keynote Events Set to Take Place at the ACS Fall 2026 Meeting?

Podcasts



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Welcome to “Analytically Speaking,” the podcast from LCGC International and Spectroscopy. Here in Episode #47, podcast host Dr. Jerry Workman speaks with Dr. Thomas Mayerhöfer from the Leibniz Institute of Photonic Technology (Leibniz IPHT) in Jena, Germany, and Friedrich Schiller University Jena, about “the other half” of the Beer–Lambert law: dispersion theory, the concentration law of the refractive index, and refractive-index and complex-valued chemometrics. Dr. Mayerhöfer, who first joined the podcast for Episode #29 on the history and theory of infrared spectroscopy, returns to explain how Beer’s law falls out of dispersion theory as a limiting case, why the refractive index obeys a concentration law of its own that was mainstream physical chemistry before about 1920 (and helped confirm the Kekulé structure of benzene), and how new refractive-index and complex-valued chemometric methods — in combination with PLS — can outperform conventional absorbance-based calibration by up to an order of magnitude.

Geochemistry in Rock layers © Daco -chronicles-stock.adobe.com

LIBS in Geosciences: A Practical Tutorial

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Laser-induced breakdown spectroscopy (LIBS) has moved from the laboratory to the field, offering rapid, in situ elemental analysis of minerals, rocks, soils, and meteorites with minimal sample preparation. This practical tutorial covers LIBS instrumentation, field sampling best practices, quantification methods, common pitfalls, and emerging applications in geoscience.

Refraction of Light Through a Solid © Graphicazzy -chronicles-stock.adobe.com

For 170 years, spectroscopists have built quantitative analysis on only one number pulled from every spectrum they ever recorded, discarding its inseparable twin. New dispersion-theory and complex-valued chemometric methods recover that missing half, the refractive index, and in favorable systems cut calibration error by as much as an order of magnitude.

Cellular autofluorescence often masks target signals in time-resolved fluorescence imaging, and metal-based phosphors that could solve this raise toxicity and cost concerns. Thermally activated delayed fluorescence (TADF) materials offer a metal-free alternative with long emission lifetimes, and early studies show promise despite remaining challenges with quenching, solubility, and spectral purity.

Traditional Blood Glucose Meter © pittawut -chronicles-stock.adobe.com

Nearly every diabetic on earth still stabs a finger to measure their blood sugar, but a small army of lasers, infrared beams, and machine-learning algorithms is quietly plotting to end that ritual for good. This review tracks the photons chasing glucose through skin, from near-infrared reflectance to Raman fingerprints, and asks why the “needle-free” promise keeps slipping just out of reach.

Linear Regression Trend Line Plot ©  Safeer -chronicles-stock.adobe.com

A technical white paper deriving the classical least squares (CLS) and weighted least squares (WLS) models and showing how generalized least squares (GLS) and extended least squares (ELS) extend CLS to provide clutter suppression for characterized interference signals in spectroscopic and hyperspectral measurements.

Close up of artist’s rendition of a handheld spectrometer ©  whitestorm -chronicles-stock.adobe.com

Spectrometers that once filled an entire lab bench now fit in a coat pocket, and they are quietly reshaping how fentanyl gets identified on a roadside, how counterfeit cashmere gets caught on a loading dock, and how a five-hundred-year-old painting gets authenticated without ever leaving the wall. This review tracks five years of coverage from Spectroscopy alongside the broader literature to show how handheld Raman, FT-IR, NIR, and XRF instruments moved from laboratory novelty to field necessity.