The following articles are the most accessed digital object identifier (DOI) manuscripts for Spectroscopy and LCGC International during the month of August 2026. Ten articles are individually ranked here by DOI page views.
|Articles|November 1, 2014
- Spectroscopy E-Books-11-01-2014
- Volume e2
- Issue 3
Analytical Tools for the Characterization of Biopharmaceuticals: Mass Spectrometric Detection
Author(s)Sarah Cianferani
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A complete set of mass spectrometry tools is available for mAb characterization, and includes bottom-up approaches, middle-up analysis of mAb fragments, and intact mAb analysis. In some cases, these tools are being coupled with chromatographic separation methods while in others they are being used with innovative techniques such as native MS and native ion mobility mass analysis. In particular, native MS techniques can play a key role in the characterization of higher-order structures. Read more
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Articles in this issue
almost 12 years ago
Analyzing Carbohydrates on Therapeutic GlycoproteinsAdvertisement
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The bulky bench-top NIR spectrometer is quietly being dismantled and rebuilt as a wafer-scale photonic chip, a self-calibrating algorithm, and a sensor small enough to ride in a shirt pocket. What once demanded a grating, a moving mirror, and a climate-controlled lab now fits inside a handheld module, a bioreactor probe, or a drone payload, and it increasingly figures out what it is looking at on its own.
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