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Articles

Professor Rohit Bhargava and his team at the University of Illinois, where they have established the Cancer Center at Illinois, are advancing research in tumor microenvironments, using techniques such as high-definition Fourier transform infrared (HD-FT-IR) coupled with machine learning. We recently spoke to Bhargava about this work. 

High-Definition Fourier Transform Infrared Spectroscopic Imaging of the Tumor Microenvironment

Those inexperienced in using FT-IR spectrometers can encounter problems when measuring spectra. This article discusses several main issues that most users experience while using FT-IR spectrometers and how to remedy each problem.

Common Problems with FT-IR Instruments and How to Avoid Them

Here, we finish a discussion of the spectrum of polyethylene (PE) and explore
how different PE syntheses produce materials with different physical and
spectroscopic properties.

The Infrared Spectra of  Polymers II: Polyethylene

Peak shifts in infrared spectra may occur for many reasons other than structural changes on the molecular or unit cell level. Here, we discuss several examples.

Five Reasons Why Not Every Peak Shift in Infrared (IR) Spectra Indicates a Chemical Structure Change

Jerome Workman Jr. serves on the Editorial Advisory Board of Spectroscopy and is currently with Unity Scientific LLC. He is also an adjunct professor at Liberty University and U.S. National University. He can be reached at jworkman04@gsb.columbia.edu.

Igor K. Lednev at the University at Albany SUNY in New York explains advances in forensic analysis using a variety of chemometrics techniques to classify ATR FT-IR and Raman spectra of bodily fluids.

Forensics Applications of Raman Spectroscopy, ATR FT-IR, and Chemometrics

Infrared nanoscopy is a valuable new spectroscopy tool for exploring the nanoscale of materials science. Mun Seok Jeong of Sungkyunkwan University in Korea explains.

Advancing Spectroscopy into the Nanoworld of Materials Science: Vibrational Nanoscopy and Infrared Nanoscopy

Inline FT-NIR and offline terahertz Raman imaging analysis are used to characterize active pharmaceutical ingredient (API) crystallinity and to monitor different solid physical states of the API, to control process parameters of hot melt extrusion.

Solid Physical State Transformation in Hot Melt Extrusion Revealed by Inline Near-Infrared (NIR) Spectroscopy and Offline Terahertz (THz) Raman Imaging

Resonant SEIRA overcomes the limitations of traditional Fourier transform infrared (FT-IR) spectroscopy for minute sample sizes of relatively low absorptivity.
Frank Neubrech of Heidelberg University is exploring resonant SEIRA in applications such as monitoring dynamic processes and hyperspectral infrared chemical imaging.

Resonant Surface-Enhanced Infrared Spectroscopy (Resonant SEIRA) Using Metal Nanoantennas

Polymers contain practically every infrared functional group imaginable. Now that we understand infrared functional groups from previous articles, it is time to look at the spectra of polymers in greater detail.

The Infrared Spectra of Polymers, Part I: Introduction

We show how FT-IR may be used for quality control analysis of natrii sulfas, a transparent crystalline material used in natural medicine that primarily contains sodium sulfate decahydrate, crystallized from sulfate minerals.

Infrared (IR) Spectroscopy