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Articles

Our annual review of new products for atomic and molecular spectroscopy, including details by category and highlights of overarching trends.

2022 Review of Spectroscopic Instrumentation

Salvatore La Cavera III and his colleagues in the Faculty of Engineering at the University of Nottingham, in Nottingham, United Kingdom have developed a novel measurement system consisting of two ultrafast lasers that excite and detect high-frequency ultrasound from a nano-transducer fabricated onto the tip of a single-mode optical fiber. 

Phonon Imaging in 3D with a Fiber Probe

Professor Rohit Bhargava and his team at the University of Illinois, where they have established the Cancer Center at Illinois, are advancing research in tumor microenvironments, using techniques such as high-definition Fourier transform infrared (HD-FT-IR) coupled with machine learning. We recently spoke to Bhargava about this work. 

High-Definition Fourier Transform Infrared Spectroscopic Imaging of the Tumor Microenvironment

This article discusses coherent Raman imaging and how it can visualize and quantify cutaneous pharmacokinetics (PK). 

Coherent Raman Imaging for Assessing Cutaneous Pharmacokinetics: Advancements and Outlook

Inline FT-NIR and offline terahertz Raman imaging analysis are used to characterize active pharmaceutical ingredient (API) crystallinity and to monitor different solid physical states of the API, to control process parameters of hot melt extrusion.

Solid Physical State Transformation in Hot Melt Extrusion Revealed by Inline Near-Infrared (NIR) Spectroscopy and Offline Terahertz (THz) Raman Imaging

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Recent technical advances in biomedical Raman imaging pave a way to its application in the biomedical fields, where morphological information of samples provides rich information. A recent technical conference in Osaka, Japan, explored these developments.

Biomedical Raman Imaging 2019 in Osaka

An SPR experiment is composed of several steps, from ligands immobilization to data analysis. Results can be reached using a SPRi system for real time and label-free, specific and sensitive interactions.

How to Start an SPRiExperiment

Surface Plasmon Resonance imaging (SPRi) instruments enable a large number of different label-free molecular interactions to be monitored simultaneously and in parallel in a single experiment. This multiplexing capability will be demonstrated using an antibody SPRi-Biochip™.

Multiplexed Detection of Antigens Using an Antibody Biochip

Taking advantage of the multiplexing capabilities of SPR imaging, combined
with the flexibility of the SPRi-Arrayer can help speed up the optimization steps necessary prior to kinetics analysis.