Column: Atomic Perspectives

Advances in Trace Element Solid Sample Analysis: Laser Ablation Laser Ionization TOF Mass Spectrometry (LALI-TOF-MS)

May 01, 2020

Recent advances in laser ablation laser ionization TOF mass spectrometry (LALI-TOF-MS) are allowing laboratories to reach required limits of quantitation for trace impurities in solid materials by direct analysis, while avoiding common limitations of other techniques.

Integrated Analysis of In-Service Lubricants for Particle Size and Count and Metal Content in a Single Sample Run

March 01, 2020

By placing a liquid particle counter in-line with an ICP-OES system it is possible to analyze wear metals and particles in lubricant samples in one run. This approach streamlines the monitoring of in-service lubricants and meets the ASTM D5185 standard. Such analyses are critical for heavy machinery maintenance.

Strategies for Achieving the Lowest Possible Detection Limits in ICP-MS

October 01, 2019

A laminar flow box for sampling is combined with a positive voltage on the skimmer cone to reduce detection limits to pg/L concentrations in ICP-MS. These improvements reduce the risk of contamination and increase the efficiency of ion sampling and focusing.

Rapid Multielement Nanoparticle Analysis Using Single-Particle ICP-MS/MS

May 01, 2019

Complex isobaric and polyatomic spectral interferences can be mitigated using triple quadrupole ICP-MS (ICP-MS/MS) with a collision–reaction cell (CRC). This configuration allows for the multielement characterization and detection of smaller nanoparticle sizes.

The Impact of Illegal Artisanal Gold Mining on the Peruvian Amazon: Benefits of Taking a Direct Mercury Analyzer into the Rain Forest to Monitor Mercury Contamination

February 01, 2019

Illegal artisanal gold mining using mercury amalgamation is poisoning people and the ecosystem in the Amazon rain forest. By taking the technique of direct mercury analysis to a remote, field-based laboratory, the team of Professor Luis Fernandez is measuring the extent of the contamination in a wide variety of samples, including soil, fish, air and human hair.

The Critical Role of Atomic Spectroscopy in Understanding the Links Between Lead Toxicity and Human Disease

October 01, 2018

With analytical advances, the clinical practice threshold for lead has dropped from 60 to 5 μL/dL.

Measuring the Metal Content of Crude and Residual Fuel Oils by EDXRF: A Rapid, Alternative Approach to ICP-OES

July 01, 2018

This study explores the possibility of measuring the metal content of crude oils using EDXRF in samples as received in both the direct and indirect excitation mode.

From Heavy Metals Testing to the Measurement of Elemental Impurities in Pharmaceuticals: Over 100 Years in Making the Change

May 01, 2018

A look at the implementation of the new United States Pharmacopeia (USP) chapters and the International Conference for Harmonization (ICH) guidelines for elemental impurities from an historical perspective, providing insight into the changes and considering the challenges and opportunities that lie ahead as the industry embraces the new methodology.

Choosing the Right Atomic Spectroscopic Technique for Measuring Elemental Impurities in Pharmaceuticals: A J-Value Perspective

March 01, 2018

How to select the optimum atomic spectroscopic technique for orally delivered drugs, based on the J-values described in the validation protocols outlined in USP Chapter