Recent advances in laser ablation laser ionization TOF mass spectrometry (LALI-TOF-MS) are allowing laboratories to reach required limits of quantitation for trace impurities in solid materials by direct analysis, while avoiding common limitations of other techniques.
By placing a liquid particle counter in-line with an ICP-OES system it is possible to analyze wear metals and particles in lubricant samples in one run. This approach streamlines the monitoring of in-service lubricants and meets the ASTM D5185 standard. Such analyses are critical for heavy machinery maintenance.
A laminar flow box for sampling is combined with a positive voltage on the skimmer cone to reduce detection limits to pg/L concentrations in ICP-MS. These improvements reduce the risk of contamination and increase the efficiency of ion sampling and focusing.
Complex isobaric and polyatomic spectral interferences can be mitigated using triple quadrupole ICP-MS (ICP-MS/MS) with a collision–reaction cell (CRC). This configuration allows for the multielement characterization and detection of smaller nanoparticle sizes.
Illegal artisanal gold mining using mercury amalgamation is poisoning people and the ecosystem in the Amazon rain forest. By taking the technique of direct mercury analysis to a remote, field-based laboratory, the team of Professor Luis Fernandez is measuring the extent of the contamination in a wide variety of samples, including soil, fish, air and human hair.
A look at the implementation of the new United States Pharmacopeia (USP) chapters and the International Conference for Harmonization (ICH) guidelines for elemental impurities from an historical perspective, providing insight into the changes and considering the challenges and opportunities that lie ahead as the industry embraces the new methodology.