April 10th 2024
A recent study used spectroscopic techniques to quantify telmisartan and rosuvastatin in tablet dosage form and plasma.
ATR-FT-IR Spectroscopy Offers a New Cost-effective Method for Pharmaceutical Heparin Analysis
April 17th 2023In a recent study, attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FT-IR) was proven to be a cost-effective method for analyzing herapins in pharmaceutical applications.
Process Analytical Technology (PAT) Model Lifecycle Management
March 1st 2023The accuracy of prediction models based on spectroscopic measurements can be influenced by a variety of factors, including aging equipment. Continuous monitoring is key to managing the PAT model lifecycle and ensuring that changes over time do not negatively affect prediction model performance.
Solvent Assisted Ionization Mass Spectrometry for Screening and Quantification of Counterfeit Drugs
July 1st 2015Because of the wide variety of ways counter drugs have been entering the pharmaceutical supply chain, there is an imminent need for quick and inexpensive methods to identify drug components and quantify active ingredients. Here, we report results illustrating the screening properties of solvent assisted ionization mass spectrometry (SAI-MS) and the quantitative properties of liquid chromatography (LC)-SAI-MS. These methods offer high sensitivity, versatility, and in combination, rapid turnaround time. Suspect samples of fexofenadine hydrochloride and hydroxychloroquine were rapidly screened and compared to their legal counterparts using SAI-MS.