Pharmaceutical Analysis

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Top articles published this week include a peer-reviewed article that discuss two multivariate calibration algorithms for the spectrophotometric analysis of a drug containing antazoline hydrochloride (AN) and naphazoline hydrochloride (NP), an article about chemometric calibrations, and a feature about the 2024 Emerging Leader in Molecular Spectroscopy awardee.

Eye drops medicine bottle with pharmacy store shelves background | Image Credit: © Kwangmoozaa - stock.adobe.com.

This study applied principal component regression (PCR) and partial least squares (PLS) algorithms for the spectrophotometric analysis of a drug containing antazoline hydrochloride (AN) and naphazoline hydrochloride (NP) without chemical separation. Both methods showed high accuracy and precision, with results closely matching those from a reference HPLC method, and were successfully validated for analyzing commercial pharmaceutical products.