Surface-enhanced Raman spectroscopy (SERS)

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Yukihiro Ozaki
Tip-enhanced Raman Scattering using a Chemically-modified Tip

June 9th 2025

In this tutorial article, Yukihiro Ozaki explores the recent advancements and broadening applications of tip-enhanced Raman scattering (TERS), a cutting-edge technique that integrates scanning probe microscopy (SPM) with surface-enhanced Raman scattering (SERS). TERS enables highly localized chemical analysis at the nano- to subnano-scale, achieving spatial resolution well beyond the diffraction limit of light. Ozaki highlights the versatility of TERS in various experimental environments—ranging from ambient air to ultrahigh vacuum and electrochemical systems—and its powerful utility in fields such as single-molecule detection, biomolecular mechanism studies, nanomaterial characterization, and high-resolution imaging.

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New Insight into Brain Peptide Dynamics Unlocked by Advanced Spectroscopy

June 4th 2025

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Machine Learning Accelerates Clinical Progress of SERS Technology

May 22nd 2025

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New SERS Platform Enhances Real-Time Detection of Cardiovascular Drugs in Blood

May 13th 2025

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The Rise of Smart Skin Using AI-Powered SERS Wearable Sensors for Real-Time Health Monitoring

May 5th 2025

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