July 21st 2025
This tutorial addresses the critical issue of analyte specificity in multivariate spectroscopy using the concept of Net Analyte Signal (NAS). NAS allows chemometricians to isolate the portion of the signal that is unique to the analyte of interest, thereby enhancing model interpretability and robustness in the presence of interfering species. While this tutorial introduces the foundational concepts for beginners, it also includes selected advanced topics to bridge toward expert-level applications and future research. The tutorial covers the mathematical foundation of NAS, its application in regression models like partial least squares (PLS), and emerging methods to optimize specificity and variable selection. Applications in pharmaceuticals, clinical diagnostics, and industrial process control are also discussed.
5th Annual Mole Spectroscopy in Practice: Molecular Spectroscopy Inside and Outside of the Lab
June 30th 2025Webinar Date/Time: Wednesday, July 23rd, 2025 Morning Session: 11:00 am EDT - 1:00 pm EDT Afternoon Session: 2:00 pm EDT - 3:00 pm EDT Thursday, July 24th, 2025 Morning Session: 11:00 am EDT - 1:00 pm EDT Afternoon Session: 2:00 pm EDT - 3:00 pm EDT
How Do We Improve Elemental Impurity Analysis in Pharmaceutical Quality Control?
May 16th 2025In this final part of our conversation with Harrington and Seibert, they discuss the main challenges that they encountered in their study and how we can improve elemental impurity analysis in pharmaceutical quality control.
How do Pharmaceutical Laboratories Approach Elemental Impurity Analysis?
May 14th 2025Spectroscopy sat down with James Harrington of Research Triangle Institute (RTI International) in Research Triangle Park, North Carolina, who was the lead author of this study, as well as coauthor Donna Seibert of Kalamazoo, Michigan. In Part I of our conversation with Harrington and Seibert, they discuss the impact of ICH Q3D and United States Pharmacopeia (USP) <232>/<233> guidelines on elemental impurity analysis and how they designed their study.
LIBS Illuminates the Hidden Health Risks of Indoor Welding and Soldering
April 23rd 2025A new dual-spectroscopy approach reveals real-time pollution threats in indoor workspaces. Chinese researchers have pioneered the use of laser-induced breakdown spectroscopy (LIBS) and aerosol mass spectrometry to uncover and monitor harmful heavy metal and dust emissions from soldering and welding in real-time. These complementary tools offer a fast, accurate means to evaluate air quality threats in industrial and indoor environments—where people spend most of their time.
Atomic Perspectives: Highlights from Recent Columns
March 3rd 2025“Atomic Perspectives,” provides tutorials and updates on new analytical atomic spectroscopy techniques in a broad range of applications, including environmental analysis, food and beverage analysis, and space exploration, to name a few. Here, we present a compilation of some of the most popular columns.
Pittcon 2025: Highlighting Talks on Atomic Spectroscopy
February 26th 2025At Pittcon this year, there will be numerous sessions dedicated to spotlighting the latest research that uses atomic spectroscopy or elemental analysis techniques. We highlight some of these talks below that might pique the interest of spectroscopists and researchers attending the conference this year.
The 2025 Emerging Leader in Atomic Spectroscopy Award
February 15th 2025Benjamin T. Manard has won the 2025 Emerging Leader in Atomic Spectroscopy Award for his pioneering research in nuclear material characterization and isotope ratio analysis, with expertise in advanced atomic spectrometry techniques such as inductively coupled plasma optical emission spectroscopy (ICP-OES), inductively coupled plasma mass spectrometry (ICP-MS), and laser ablation.
Applications of Micro X-Ray Fluorescence Spectroscopy in Food and Agricultural Products
January 25th 2025In recent years, advances in X-ray optics and detectors have enabled the commercialization of laboratory μXRF spectrometers with spot sizes of ~3 to 30 μm that are suitable for routine imaging of element localization, which was previously only available with scanning electron microscopy (SEM-EDS). This new technique opens a variety of new μXRF applications in the food and agricultural sciences, which have the potential to provide researchers with valuable data that can enhance food safety, improve product consistency, and refine our understanding of the mechanisms of elemental uptake and homeostasis in agricultural crops. This month’s column takes a more detailed look at some of those application areas.
Best of the Week: Seed Vigor, Flower Classification, Emerging Leader in Atomic Spectroscopy
January 10th 2025Top articles published this week include two peer-reviewed articles that explore optical detection technology for seed vigor and classifying flowers, as well as a profile on Benjamin Manard, who was recognized as the winner of the 2025 Emerging Leader in Atomic Spectroscopy.
New Study Reveals How NASA’s Perseverance Rover Uses LIBS for Precise Mars Rock Analysis
November 12th 2024NASA’s Perseverance rover is collecting valuable information for scientists back on Earth. A recent study explored how laser-induced breakdown spectroscopy (LIBS) is being used to analyze the Martian surface.
Simultaneous Determination of 50 Elements in Geological Samples by ICP-MS Combined with ICP-OES
October 15th 2024A method combining inductively coupled plasma–mass spectrometry (ICP-MS) with inductively coupled plasma–optical emission spectrometry (ICP-OES) was developed for multielement determination of 50 species of major, minor, micro, and trace, rare earth, and rare elements in geological samples.