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Mid-Infrared Emission Study Proposes New Principle for Noninvasive Blood Sugar Measurement
September 12th 2025A research team in Japan has proposed a new principle, called the emission integral effect, to explain how mid-infrared passive spectroscopic imaging can detect blood glucose levels without invasive methods. Their findings suggest that dilute components like glucose may be more identifiable than concentrated ones when using this technique.
New Infrared Device Measures Blood Sugar Without a Prick
September 11th 2025Researchers have developed a miniature non-invasive blood glucose monitoring system using near-infrared (NIR) technology. The compact, low-cost device uses infrared light to measure sugar levels through the fingertip, offering a painless alternative to traditional finger-prick tests.
Molar Absorptivity Model Powers Near-Infrared Glucose Testing
September 10th 2025Researchers from Sharif University of Technology, Tehran, present an approach using near-infrared absorbance and molar absorptivity to estimate blood glucose with a drawn blood sample—showing comparable performance to methods that apply principal components regression (PCR).
Mini-Tutorial on NIR Aquaphotomics for Rapid, Non-Destructive Biofluid and Food Analysis
September 9th 2025Near-infrared (NIR) spectroscopy combined with aquaphotomics shows potential for a rapid, non-invasive approach to detect subtle biochemical changes in biofluids and agricultural products. By monitoring water molecular structures through water matrix coordinates (WAMACs) and visualizing water absorption spectrum patterns (WASPs) via aquagrams, researchers can identify disease biomarkers, food contaminants, and other analytes with high accuracy. This tutorial introduces the principles, practical workflow, and applications of NIR aquaphotomics for everyday laboratory use.
Demystifying the Black Box: Making Machine Learning Models Explainable in Spectroscopy
September 8th 2025This tutorial provides an in-depth discussion of methods to make machine learning (ML) models interpretable in the context of spectroscopic data analysis. As atomic and molecular spectroscopy increasingly incorporates advanced ML techniques, the black-box nature of these models can limit their utility in scientific research and practical applications. We present explainable artificial intelligence (XAI) approaches such as SHAP, LIME, and saliency maps, demonstrating how they can help identify chemically meaningful spectral features. This tutorial also explores the trade-off between model complexity and interpretability.
NIR Aquaphotomics Milk Analysis Method Detects Johne’s Disease in Dairy Cows
September 4th 2025Researchers have demonstrated a non-invasive method using milk and near-infrared spectroscopy combined with Aquaphotomics to accurately detect Paratuberculosis in dairy cattle. The technique offers faster, more sensitive diagnosis than traditional methods.
Spectroscopy Guides Long-Term Conservation of Renaissance Murals in Valencia
September 4th 2025Researchers at the University of the Basque Country, along with Català Restauradors S.L. analyzed the emergence of soluble salts on mural paintings in the vault of the Valencia Cathedral, using Raman and micro-energy-dispersive X-ray fluorescence spectroscopy combined with ion chromatography.
Aquaphotomic NIR Spectroscopy Technique Could Rapidly Detect Toxic Aflatoxin in Maize
September 3rd 2025Researchers have demonstrated that visible and near-infrared spectroscopy, combined with chemometric and aquaphotomic analysis, can accurately classify and quantify aflatoxin contamination in white and yellow maize, offering a faster, non-destructive alternative to traditional methods.
NIR Aquaphotomics Blood Test Uses Light With Water Patterns to Detect Esophageal Cancer
September 2nd 2025Researchers have developed a rapid, non-invasive screening method for esophageal squamous cell carcinoma (ESCC) using near-infrared spectroscopy and aquaphotomics. The approach analyzes plasma water patterns, achieving over 95% accuracy in distinguishing patients from healthy controls
New Imaging Breakthrough Offers Hope for Early Diagnosis of Acute Mesenteric Ischemia
September 2nd 2025A recent study demonstrated that combining hyperspectral imaging with multivariate curve resolution can non-invasively detect and monitor intestinal necrosis in acute mesenteric ischemia, offering a promising tool for earlier diagnosis and improved patient outcomes.
Advancing Metabolite Identification with a Compact Infrared Ion Spectroscopy Platform
September 1st 2025Metabolite identification is critical in drug development, with mass spectrometry (MS) as the primary tool, but limited in full structural elucidation. Infrared ion spectroscopy (IRIS) overcomes some of these limitations by combining MS sensitivity with IR-based structural fingerprints, enabling characterization without reference standards. Spectroscopy spoke to Giel Berden regarding applications in metabolite identification by determining the site of glucuronidation and phase I oxidation in selected drug molecules.
Inside the Laboratory: How Computational Approaches Can Improve Understanding of Molecular Behavior
August 29th 2025In Part 2 of this “Inside the Laboratory,” feature on George Shields, a professor of chemistry at Furman University and the founder and director of the Molecular Education and Research Consortium in Undergraduate Computational ChemistRY (MERCURY), Consortium, we discuss his research into computational approaches to improve our understanding of molecular behavior in both biochemistry and atmospheric chemistry and his work applying replica exchange molecular dynamics (REMD) for breast cancer drug design.
Smarter Spectroscopy With a New Machine Learning Approach to Estimate Prediction Uncertainty
August 27th 2025A new study demonstrates how a machine learning technique, quantile regression forest, can provide both accurate predictions and sample-specific uncertainty estimates from infrared spectroscopic data. The work was applied to soil and agricultural samples, highlighting its value for chemometric modeling.
Infrared Spectroscopy Emerges as Key Tool for Identifying Plant-Based Milk Alternatives
August 26th 2025A new study demonstrates that infrared spectroscopy combined with chemometric modeling offers a fast, cost-effective way to classify plant-based milk alternatives and detect compositional variability, particularly in almond beverages.