Top articles include the publication of a new terminology guide focused on data processing, machine learning, artificial intelligence (AI), and chemometrics.

This column shows that a Raman plate reader paired with partial least squares regression can simultaneously quantify glucose, fructose, sucrose, and ethanol in yeast fermentation samples, using turbidity-matched calibration standards to correct for yeast-induced turbidity, and offers a rapid, label-free, high-throughput method for tracking sugar consumption and ethanol production in strain screening, media optimization, and process development.

This column, the second installment on highly substituted benzene rings, shows that tri- and tetra-substituted substitution patterns can be distinguished by whether the ring bending peak is present and by the position of the in-phase aryl C-H wagging peak, which shifts according to how many adjacent hydrogens the ring carries.

How do ions and water interact at the atomic level in nanochannels grafted with polymer brushes using all-atom molecular dynamics simulations? Siddhartha Das of the University of Maryland and his team are working on answering this question.

Mammograms can find breast microcalcifications but can’t tell whether they are likely benign or malignant.

In a SciX interview, Marc Porter covered a lot of ground, from a student-driven pivot into immunoassays to a baseball analogy for Stokes and anti-Stokes scattering, and shares the open questions he is still chasing.

Laser-induced breakdown spectroscopy (LIBS) is being used in numerous application areas, including environmental monitoring, cultural heritage, and space exploration.

At SciX, Kevin Wilkinson of the Universite de Montreal explains how faster data acquisition and new software have cut analysis time and how a particle’s chemical composition can link arsenic-bearing emissions back to a copper refinery’s processes.

Microspectroscopy, the marriage of spectroscopic chemical identification with microscopic spatial resolution, has advanced from Perkin-Elmer's first commercial infrared microspectrometer in 1953 to today's nanoscale AFM-IR probes, synchrotron-brightness infrared beamlines, and compact hyperspectral tissue imaging devices being developed for AI-assisted cancer detection.

The 2026 first edition of Spectroscopy's Chemometrics, Data Processing, Machine Learning, and Artificial Intelligence Terminology Guide defines the classical chemometric, statistical, machine learning, AI, and process analytical technology (PAT) terms most likely to be encountered by working spectroscopists, analytical chemists, and process engineers.

Does industry need to get more involved in training the next generation of spectroscopists?

In an interview at SciX, Alessandro De Giacomo discusses nanoparticles as signal enhancers and medical tags, a self-calibrating drone LIBS system, open questions in laser–matter interaction, and why students need a strong foundation in fundamentals.

The New York / New Jersey Section of the Society for Applied Spectroscopy will present its 2026 Gold Medal Award to Richard Crocombe at the Eastern Analytical Symposium on November 17, recognizing two decades of work that helped carry spectroscopy out of the laboratory and into the field.

Near-infrared spectroscopy combined with principal components analysis and a back propagation neural network identified Huanglongbing-infected Gannan navel orange leaves with an overall accuracy of 98.75%, outperforming LDA, KNN, and SVM models.

Top articles include an examination of the current trends propelling atomic spectroscopy forward and post-conference coverage of the 2026 SciX show in Sparks, Nevada.

In this Q&A, we recap the October edition of “What’s Nu,” which covered topics such as how novel spectroscopic and analytical methods are transforming environmental monitoring, medical treatment, and accessibility in scientific research.

In this Q&A article, we highlight several prominent researchers being recognized at the 2026 SciX Conference for their significant contributions to spectroscopy and photonics and discuss what these researchers talked about at the conference.

Amy Colleran, a Postdoctoral Researcher in the Centre of Metabolomics Research at the University of Liverpool, is exploring how to detect volatile organic compounds by bubbling them directly into colloidal silver and gold nanoparticles.

The Eastern Analytical Symposium returns to Plainsboro, New Jersey, November 16–18, with a keynote on AI-ready data and a posthumous award honoring solid-state NMR researcher Robert Schurko.

In this segment of our SciX interview with Kevin Wilkinson, a professor of environmental chemistry at the Université de Montréal, discusses extending lead isotope work to greater distances and explains why graduate students need adaptability, critical judgment, and coding skills more than expertise in any single instrument.

Atomic spectroscopy has quietly gone from counting elements in bulk to counting single nanoparticles, imaging tissue at the micrometer scale, and reading Martian rocks from several meters away. The instruments got smaller, the software got smarter, and the questions they can now answer got a lot more interesting.

At SciX, Jay Kitt discusses a project applying Raman spectroscopy to PFAS analysis, the mentoring role he found after leaving traditional academia, and why machine learning could unlock the biochemical information in vibrational spectra.

In this “Tutorial Tuesday” clip, Peter Larkin, who is a Manager of Spectroscopy, Thermal Analysis, and Chromatography at Syensqo, highlights how people use the method or technique that they are comfortable with, even if it’s not the best one to use.

UV–vis absorption spectroscopy, one of analytical chemistry's oldest and most accessible techniques, remains foundational to cutting-edge science, underpinning the Nobel Prize-winning discovery and synthesis of quantum dots and continuing to evolve through ultralow stray-light optics, chip-scale sensors, and AI-integrated process analyzers.

What are the education gaps and how will they be addressed?

Top articles include a new "Spectral Frontiers" column and post-conference coverage of the 2026 SciX show in Sparks, Nevada.

In this interview segment from SciX, Juergen Popp explains why molecular “twins” built from optical measurements could reach patients within a decade, provided the field builds the regulatory, computing, and standards ecosystem around the technology.

Siddhartha Das explains how machine learning helps his group sift through roughly a trillion simulation data points. It reveals water and electroosmotic flow behavior and could speed the design of sensor-like channels.