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A multiscale convolutional neural network (MsCNN) was used to screen Raman spectra of the hepatitis B serum, achieving higher classification accuracy compared to traditional machine learning methods.

Multiscale Convolutional Neural Network of Raman Spectra of Human Serum for Hepatitis B Disease Diagnosis

Zac Schultz of The Ohio State University and his team used tip-enhanced Raman spectroscopy (TERS) and surface-enhanced Raman spectroscopy (SERS) with gold nanostars to investigate chemical reactions involved in protein–ligand binding. He recently spoke with Spectroscopy about his findings.

Investigating Protein Receptors and Other Biomolecules Using SERS and TERS

Jerome Workman Jr. serves on the Editorial Advisory Board of Spectroscopy and is currently with Unity Scientific LLC. He is also an adjunct professor at Liberty University and U.S. National University. He can be reached at jworkman04@gsb.columbia.edu.

Bhavya Sharma is the winner of the 2021 Emerging Leader in Molecular Spectroscopy Award. We recently interviewed her about her work conducting research to detect active and important biomolecules related to hormone regulation, neurological health, and disease diagnosis.

Exploring Neurochemistry Using Raman Spectroscopy

Mark Meyerhoff has been exploring chemical sensors for biomedical applications. Because of his work, Meyerhoff has been awarded the 2021 ANACHEM award. Meyerhoff spoke to us about his work, his career, and what being presented this award at this fall’s SciX event means to him.

Developing Electrochemical and Optical Sensors to Measure Analytes in Physiological Samples

Professor Rohit Bhargava and his team at the University of Illinois, where they have established the Cancer Center at Illinois, are advancing research in tumor microenvironments, using techniques such as high-definition Fourier transform infrared (HD-FT-IR) coupled with machine learning. We recently spoke to Bhargava about this work. 

High-Definition Fourier Transform Infrared Spectroscopic Imaging of the Tumor Microenvironment

Uwe Karst of the University of Münster in Germany explains the use of laser ablation–inductively coupled plasma–mass spectrometry (LA-ICP-MS) imaging to provide spatially resolved quantification of trace elements in biological samples.

Investigating Lanthanide Deposition Patterns in Tissue Using Laser Ablation–Inductively Coupled Plasma–Mass Spectrometry (LA-ICP-MS) Imaging

This year’s molecular spectroscopy award recipient is Bhavya Sharma, who is demonstrating research leadership focused on neurochemical detection using SERS and SORS Raman spectroscopy.

The 2021 Leader in Molecular Spectroscopy Award

Investigating Lanthanide Deposition Patterns in Tissue Using LA-ICP-MS Imaging

In precious samples, effective methods for multielemental analysis could provide a deeper understanding of the essential role of elements as cofactors in biological and pathological processes. Tobias Konz of Nestlé Research explains.

Quantitative Methods for Multielemental Analysis in Low-Volume Biofluids

Medical diagnostics is an exciting area of spectroscopy research, and one of the dreams is to develop spectroscopic tools that can be used for point-of-care diagnostics with a smartphone. Russ Algar, the 2017 Emerging Leader in Molecular Spectroscopy, is one of the scientists on that quest

Biological, Medical, and Clinical Analysis