Appendix IV: Mass spectrometry
Appendix IV: Mass spectrometry
Manufacturer: Hiden Analytical Ltd
Product name: QGA Atmospheric Gas Analysis System
Mass spectrometer
New this year: The new Hiden QGA Professional gas/vapor analysis software
Used for: Lab applications
Software: QGA Professional / MASsoft 7 Professional; may be used in other equipment, compatible with other manufacturers' equipment
Special features: Provides real-time continuous and quantitative analysis of gas mixtures comprising up to 16 species and is now available for operation with all Hiden gas analysis systems.
Suggested applications: High purity gas analysis, fermentation, fuel cells, gas production and storage, environmental monitoring
Primary benefits: Appearance potential mass spectrometry, fast response times – less than 300 ms, acquisition speed up to 500 measurements/s, Hiden QIC (quartz inert capillary) sampling interface samples from 100 mbar to 2 bar
Manufacturer: Markes International Ltd.
Product name: Select-eV
Mass spectrometer
New this year: New variable-energy electron ionization for GC–MS
Special features: No loss in sensitivity for fast and accurate compound identification
Used for: Lab analysis
Unique features: Source can change the energy of ionizing electrons; this allows the production of reference-quality electron ionization mass spectra with conventional full-fragmentation patterns. Energies can be varied anywhere from standard 70 eV down to 10 eV without loss in sensitivity; sometimes signal-to-noise ratios of many compounds are increased at lower energies.
Manufacturer: Microsaic Systems plc
Product name: 4000 MiD
Portable mass spectrometer
Used for: Lab, process, handheld analysis
Dimensions: 55 x 35 x 25 cm; weight: 32 kg
Measurement mode: Full scan (m/z 50-800), SIM and simultaneous SIM/fullscan
Software: Masscape, available as separate product, may be used in other equipment, compatible with other manufacturers' equipment.
Suggested applications: Mass detection for use in prep-, analytical-, flash- LC, reaction monitoring, flow chemistry, batch reaction online analysis, process monitoring.
Primary benefits: Deployability, everything fits inside a lab fume hood. You can take the mass spectrometer to the point of need.
Unique features: Smallest footprint single quadrupole MS, uses technology based on MEMS manufacturing, Fits in a standard fume hood, No external roughing pump needed, Integrated PC, remote operation supported, No A/C or sound-proofing required; deployability in a lab.
Manufacturer: Shimadzu
Product name: LCMS-8050
Triple-quadrupole LC–MS-MS system
New this year: Multiple reaction monitoring, 5-ms polarity switching, quantitative and qualitative analysis of multiple components.
Used for: Lab analysis
Primary benefits: 5 ms polarity switching, scan rate of 30,000 u/s, 555 MRM/s, heated ESI probe, high-efficiency CID cell maintains signal intensity
Unique features: Data browser and an automated MRM optimization routine. Application-specific method packages.
Manufacturer: Waters Corporation
Product name: Waters ionKey/MS System
Mass spectrometer
Used for: Lab analysis
Measurement mode: Microfluidic device and source for mass spectrometry.
Software: Available as separate product, 21CFR11 compliant, cGMP compliant, may be used in other equipment, compatible with other manufacturers' equipment
Suggested applications: Bioanalyses, pharmacokinetic studies, food safety and environmental analyses
Primary benefits: Enhanced sensitivity, plug and play nature: the Waters iKey separation device is designed so that all it takes is a few seconds for a scientist to insert it into the source of the mass spectrometer and with the turn of a key, make the fluidic and electric connections and lock it into place.
Unique features: The ionKey/MS System's iKey microfluidic separation device contains the fluidic connections, electronics, ESI interface, column heater, eCord Intelligent Chip technology and the 1.7-μm UPLC-grade particles packed inside a 150-μm i.d. channel. Stores the iKey device's dimensions, chemistry type, serial no., manufacturing and QC history on a unique eCord chip. Waters is offering several 1.7-μm UPLC grade particles for the ionKey/MS system available in 5 cm and 10 cm pathlengths: C18 BEH (Bridged Ethyl Hybrid) 300 Å, CSH (Charged Surface Hybrid), C18 BEH 130 Å
Best of the Week: SciX Award Interviews, Tip-Enhanced Raman Scattering
June 13th 2025Top articles published this week include an interview about aromatic–metal interactions, a tutorial article about the recent advancements in tip-enhanced Raman spectroscopy (TERS), and a news article about using shortwave and near-infrared (SWIR/NIR) spectral imaging in cultural heritage applications.
Hyperspectral Imaging for Walnut Quality Assessment and Shelf-Life Classification
June 12th 2025Researchers from Hebei University and Hebei University of Engineering have developed a hyperspectral imaging method combined with data fusion and machine learning to accurately and non-destructively assess walnut quality and classify storage periods.
