Five arsenic species, including the toxicologically relevant inorganic forms As(III) and As(V), were determined in 4 minutes, with excellent sensitivity, accuracy and precision using an Agilent LC fitted with a reversed phase column coupled to an ICP-MS. Any potential interferences on As such as ArCl+ were removed using a single-cell gas mode (helium mode), speeding up the analysis.
Real-Time Chemometric Analysis of Multicomponent Bioprocesses Using Raman Spectroscopy
In this study, a glycerol-fed, lab-scale E. coli bioprocess producing representative pharmaceutical compounds was monitored offline with a portable, high-sensitivity Raman spectrometer.