Special Issues-07-01-2012

A discovery-based, untargeted metabolomics analysis of hundreds of yeast metabolites under robust, controlled extraction conditions followed by identification is described.

Nitrile rubber materials were studied using flash analytical pyrolysis-GC–MS to demonstrate that this technique is a good tool to identify the additives in nitrile rubber.

Liquid chromatography–mass spectrometry (LC–MS) successfully differentiated transgenic from native protein in a case where the proteins were highly homologous and could not be differentiated by traditional methods. This methodology may be useful for other studies of transgenic crops.

The main limitations of quantification using MALDI imaging are discussed and the different approaches used for quantitative measurement in MSI are evaluated.

DIP–MS is a fast and easy tool that can identify classes of compounds in opportunity crudes (heavy and ultraheavy crude oils, asphaltenes, and tar sands) in the field, without prior separation or treatment. It may enable fast screening of real samples to make a rough evaluation of the potential of reservoirs and oil fields.

A brief historical overview of DMS, followed by a synopsis of the instrumentation, physics, and chemistry behind the separation principles

Click the title above to open the July 2012 issue of Current Trends in Mass Spectrometry, Volume 10, Number 3, in an interactive PDF format.