Spectroscopy-05-01-2011

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Liquid chromatography–mass spectrometry (LC–MS) is a very powerful analytical technique that combines two dimensions of separation techniques. It is finding a rapidly growing demand from water analysis applications due to the increasing need to monitor water for new potential contaminants at very low levels. Despite very strong continued growth in the area, competition is already fairly concentrated among the top several competitors.

In the last four columns we described the theory of what should happen when we perform classical least squares calculations on mixtures when Beer's law applies. In this column we take our first look at what actually does happen.

Most analytical measurements performed by either inductively coupled plasma–optical emission spectrometry (ICP-OES) or ICP–mass spectrometry (MS) require accuracy and precision, which are essential for obtaining correct answers. However, all modern ICP-OES and ICP-MS instruments have the ability to perform semiquantitative analyses. This seems strange since accuracy is important, but semiquantitative analysis does have a role in analytical measurements. This article will explore why semiquantitative analysis is important and will look at various ways it can be performed and implemented.

Click the title above to open the Spectroscopy May 2011 regular issue, Vol 26 No 5, in an interactive PDF format.