Spectroscopy-06-01-2003

Oregon Health and Science University (OHSU, Portland) has proposed a research and academic program in chemical biology in which chemists and biologists work next to each other, in the same facility, on drug discovery projects.

This first installment in a series about challenges and pitfalls in interpreting data from hyphenated techniques explores general concepts in initial approaches.

The author discusses an alternative to filament sources when working with electron ionization.

The authors discuss the use of serial coulometric flow cells coupled online with electrospray ionization mass spectrometry in predictive assays for absorption, distribution, metabolism, excretion, toxicity (ADME/Tox), and stability implemented at early stages of drug discovery.