Spectroscopy-11-01-2006

Spectroscopy

Market Profile: Lifetime Fluorescence

November 01, 2006

Departments

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Lifetime fluorescence is a significant niche market within the larger category of fluorescence spectroscopy. Although the current scope of application is fairly limited, the potential is quite significant. The range of competition in this area is fairly small, but is expanding.

Validation of Spectrometry Software: A Suggested Integrated Approach to Equipment Qualification and Computerized System Validation

November 01, 2006

Focus on Quality

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Columnist Bob McDowall proposes an integrated approach to the combined issue of equipment qualification and computerized system validation for spectrometers that combines the qualification, day-to-day calibration, and maintenance of the instrument with the validation of the software for a system?s intended purpose.

Raman Spectroscopy for Cancer Diagnosis

November 01, 2006

Articles

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November 2006. Raman spectroscopy is a promising new tool for noninvasive, real-time diagnosis of tissue abnormalities. Here, we show evidence of its application for cancer diagnosis in four distinct tissue types: skin, breast, gastrointestinal tract, and cervix. Multivariate statistical analysis and discrimination algorithms allow for automated classification of the spectra into clinically relevant pathological categories using histology as a gold standard. Although limitations exist, the technique shows every indication of being an exciting prospect in the management of cancer in a clinical setting.