Spectroscopy E-Books
Historically, ion-exchange chromatography and size-exclusion chromatography (SEC) have been the reference techniques for the physicochemical characterization of biopharmaceutical compounds. However, reversed-phase liquid chromatography is naturally more compatible with mass spectrometry detection. This article discusses new trends in the use of ion-exchange chromatography and SEC, as well as the power of using ultrahigh-pressure liquid chromatography (UHPLC) and advanced reversed-phase LC columns, including sub-2-µm wide-pore porous particles or core–shell particles, for biopharmaceutical characterization. Read more
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Spectroscopy Expected to Drive Growth in $107B Proteomics Market
November 23rd 2023High-resolution magnetic angle spinning nuclear magnetic resonance (HRMAS NMR) spectroscopy in particular can be applied to nonconventional solvents, helping to obtain information about protein crystal structures while also adhering to green analytical chemistry tenets.