Top articles this week on Spectroscopy covered topics such as Raman spectroscopy in cultural heritage applications, surface-enhanced Raman spectroscopy (SERS) in pesticide detection, and the impact of artificial intelligence on spectroscopy.
This week, Spectroscopy published a variety of articles on the hottest topics in analytical spectroscopy. These news articles cover various industries and a wide range of spectroscopic techniques. Below, we’ve highlighted some of the most popular articles, according to our readers and subscribers. Happy reading!
This week, Spectroscopy Magazine published an interview with Benjamin T. Manard of the Chemical Sciences Division at Oak Ridge National Laboratory. Manard was this year’s recipient of the Lester W. Strock Award, which he will receive at the SciX Conference this October, which takes place in Raleigh, North Carolina (1). Our conversation with Manard is the first of many SciX interviews that Spectroscopy is conducting leading up to the conference.
Revolutionizing Analytical Chemistry: The AI Breakthrough
Artificial intelligence is taking the spectroscopy field by storm. This study explores AI's advancements, challenges, and future directions in the field, emphasizing its transformative potential and the need for ethical considerations (2). Although it has helped spur advancements in data interpretation and technological innovation, there are several challenges that remain.
Raman Spectroscopy Transforms Cultural Heritage and Forensic Analysis
The editors of Spectroscopy reported on a recent special issue in the Journal of Raman Spectroscopy that explored how Raman spectroscopy is being used in applications involving cultural heritage. The collection of papers in this special issue were categorized into one of the following areas: application of multivariate statistical analysis to Raman spectra, use of mobile instrumentation directly in situ for both cultural and forensic contexts, tackling optics and spectral range issues, and coupling mobile instrumentation with other complementary analytical techniques (3). The papers in this journal demonstrated that by using multivariate statistical analysis, mobile instrumentation, and novel optical techniques, these advancements offer new perspectives for studying cultural heritage and forensic evidence.
Revolutionary SERS Imaging Technique Enhances Pesticide Detection in Crops
A recent study explores how the agriculture industry could benefit from using a new surface-enhanced Raman spectroscopy (SERS) technique to detect pesticide residue in crops. Two agricultural pesticides were studied here: organophosphorus-based dimethoate (DIM) and pyrethroid-based cypermethrin (CYP) (4).
Exploring the Relationship Between Ancient Egypt and Spectroscopy: A Look at Recent Studies
Ancient Egypt was a civilization that thrived thousands of years ago before the Roman conquered them in 30 B.C. Currently, there are many ongoing archaeological excavations taking place, which help instruct us on the social, economic, and the political events that took place (5). The finding, and subsequent study, of ancient artifacts tells us so much about what Egyptian society back then was like, offering us valuable insight to the social and political structures that existed back then (5). This week, we compiled a few recent studies to show how spectroscopic techniques are being used to teach us more about Ancient Egypt.
(1) Chasse, J. Quantifying Platinum Binding on Protein-Functionalized Magnetic Microparticles with Single Particle-ICP-TOF-MS: An Interview with Stock Award Recipient Benjamin T. Menard. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/quantifying-platinum-binding-on-protein-functionalized-magnetic-microparticles-with-single-particle-icp-tof-ms-an-interview-with-stock-award-recipient-benjamin-t-menard (accessed 2024-07-11).
(2) Workman, Jr., J. Revolutionizing Analytical Chemistry: The AI Breakthrough. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/revolutionizing-analytical-chemistry-the-ai-breakthrough (accessed 2024-07-11).
(3) Workman, Jr., J. Raman Spectroscopy Transforms Cultural Heritage and Forensic Analysis. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/raman-spectroscopy-transforms-cultural-heritage-and-forensic-analysis (accessed 2024-07-11).
(4) Wetzel, W. Revolutionary SERS Imaging Technique Enhances Pesticide Detection in Crops. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/revolutionary-sers-imaging-technique-enhances-pesticide-detection-in-crops (accessed 2024-07-11).
(5) Wetzel, W. Exploring the Relationship Between Ancient Egypt and Spectroscopy: A Look at Recent Studies. Spectroscopy. Available at: https://www.spectroscopyonline.com/view/exploring-the-relationship-between-ancient-egypt-and-spectroscopy-a-look-at-recent-studies (accessed 2024-07-11).
Tip-enhanced Raman Scattering using a Chemically-modified Tip
June 9th 2025In this tutorial article, Yukihiro Ozaki explores the recent advancements and broadening applications of tip-enhanced Raman scattering (TERS), a cutting-edge technique that integrates scanning probe microscopy (SPM) with surface-enhanced Raman scattering (SERS). TERS enables highly localized chemical analysis at the nano- to subnano-scale, achieving spatial resolution well beyond the diffraction limit of light. Ozaki highlights the versatility of TERS in various experimental environments—ranging from ambient air to ultrahigh vacuum and electrochemical systems—and its powerful utility in fields such as single-molecule detection, biomolecular mechanism studies, nanomaterial characterization, and high-resolution imaging.
Machine Learning Accelerates Clinical Progress of SERS Technology
May 22nd 2025A new review in TrAC Trends in Analytical Chemistry by Alfred Chin Yen Tay and Liang Wang highlights how machine learning (ML) is transforming surface-enhanced Raman spectroscopy (SERS) into a powerful, clinically viable tool for rapid and accurate medical diagnostics.
New SERS Platform Enhances Real-Time Detection of Cardiovascular Drugs in Blood
May 13th 2025Researchers at Harbin Medical University recently developed a SERS-based diagnostic platform that uses DNA-driven “molecular hooks” and AI analysis to enable real-time detection of cardiovascular drugs in blood while eliminating interference from larger biomolecules.
The Rise of Smart Skin Using AI-Powered SERS Wearable Sensors for Real-Time Health Monitoring
May 5th 2025A new comprehensive review explores how wearable plasmonic sensors using surface-enhanced Raman spectroscopy (SERS) are changing the landscape for non-invasive health monitoring. By combining nanotechnology, AI, and real-time spectroscopy analysis to detect critical biomarkers in human sweat, this integration of nanomaterials, flexible electronics, and AI is changing how we monitor health and disease in real-time.
AI-Powered SERS Spectroscopy Breakthrough Boosts Safety of Medicinal Food Products
April 16th 2025A new deep learning-enhanced spectroscopic platform—SERSome—developed by researchers in China and Finland, identifies medicinal and edible homologs (MEHs) with 98% accuracy. This innovation could revolutionize safety and quality control in the growing MEH market.