News|Articles|October 9, 2025

Best Practices for Optimizing ICP-MS Analytical Methodology: Impact of the Evolving Application Landscape

Author(s)Robert Thomas

Explore essential best practices for optimizing ICP-MS methodologies, enhancing accuracy, and tackling analytical challenges in diverse sample matrices.

I’m honored to be the editor of this special ICP-MS supplement for Spectroscopy magazine. It gives me the opportunity to focus on what I believe is largely being ignored in the open literature—educational material that can be easily understood and used by novices or someone who has limited experience in using the technique and wants to get the most out of their instrument. We see a multitude of applications that promote the high-performance capabilities of inductively coupled plasma–mass spectroscopy (ICP-MS) using triple quads and all the innovative bells and whistles that vendors like to sell, but there are very few publications that make life easier for the ICP-MS practitioner who just has a standard system and wants to optimize their analysis.