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Robert Thomas
Articles
Regulating Heavy Metals in Baby Food: The Challenges of Food Manufacturers and the FDA Being on the Same Page
June 30, 2021
A recent investigation found dangerous levels of heavy metals in commercial baby foods. Tighter scrutiny and regulations are needed.
Single-Cell Analysis by Inductively Coupled Plasma–Time-of-Flight Mass Spectrometry to Quantify Algal Cell Interaction with Nanoparticles by Their Elemental Fingerprint
October 01, 2020
This method detects elements intrinsically present in cells, and because sc-ICP-TOF-MS measures a full mass spectrum, no analytes are missed.
Multi-Quadrupole ICP-MS: Pushing Limits of Detection to the Next Decimal
September 01, 2020
For a number of elements, spectroscopic interferences can have a significant impact on the ability to achieve low detection limits in ICP-MS. We investigate the mechanisms in multi-quadrupole ICP-MS that are designed to remove these interferences.
Choosing the Right Atomic Spectroscopic Technique for Measuring Elemental Impurities in Pharmaceuticals: A J-Value Perspective
March 01, 2018
How to select the optimum atomic spectroscopic technique for orally delivered drugs, based on the J-values described in the validation protocols outlined in USP Chapter
Handheld X-ray Diffraction for Remote, Field-Based Applications
July 01, 2015
This installment describes the development of two novel X-ray diffraction (XRD) techniques that enable the rapid analysis of samples using handheld instrumentation for remote applications. Both techniques can be applied to unprepared samples in the field, which is a highly favorable characteristic in many applications since the time required for laboratory-based sample preparation is avoided.
Determining Elemental Impurities in Pharmaceutical Materials: How to Choose the Right Technique
March 01, 2015
This installment evaluates the application requirements for the determination of 15 elemental impurities in pharmaceutical materials as described in the new United States Pharmacopeia (USP) Chapters and and offers suggestions about which atomic spectroscopic technique might be the most suitable to use.
An Investigation into the Use of Alternate Carrier Gases for the Determination of Volatile Organic Compounds in Water by GC–MS
March 01, 2015
This study focuses on United States Environmental Protection Agency (US EPA) Method 524.3 for volatile organic compounds (VOCs) in water using gas chromatography–mass spectrometry (GC–MS).
The Use of Portable and Handheld Raman Spectroscopy for Forensic Investigations
June 01, 2014
The Raman technique is gaining widespread acceptance as an investigative tool for forensic applications.
Emerging Technology Trends in Atomic Spectroscopy Are Solving Real-World Application Problems
March 14, 2014
A look at ICP–MS, ICP–OES, X-ray fluorescence spectroscopy, and laser-induced breakdown spectroscopy in the areas of research and development, marketing, application, and use of these techniques.
The Use of Raman Spectroscopy in Cancer Diagnostics
February 01, 2014
Both Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) are proving to be invaluable tools in the field of biomedical research and clinical diagnostics.