Chemometrics in Spectroscopy ? Linearity in Calibration: Quantifying Nonlinearity, Part II (PDF)

FT-IR spectroscopy, long treated as a mature bench technique for confirming a carbonyl stretch or fingerprinting a polymer, has quietly become one of chemistry’s most versatile discovery engines: it now infers molecular structure straight from a spectrum without a reference library, resolves chemistry tens of nanometers wide, and screens a fingerstick of blood for disease in minutes. The last five years of published research show FT-IR moving from a confirmatory tool into a predictive, autonomous, and field-ready analytical platform.

Raman spectroscopy is entering one of its most consequential periods since its commercialization, driven by artificial intelligence, coherent heterodyne detection, and radical instrument miniaturization, with new deep-learning frameworks and portable systems moving Raman analysis into fields, factories, and crime scenes.

In this Q&A overview, we explore the derivation of principal component analysis using elementary algebra rather than standard matrix notation.

A new review article in Microchimica Acta finds that smartphone-based optical and spectroscopic sensors show strong potential to decentralize food safety testing across contaminants like pesticides, heavy metals, and pathogens.

Raman spectroscopy just got a brain, a stopwatch, and a nose. Together, these upgrades are turning a century-old light-scattering trick into a frontline tool for catching cancer earlier, chiral drugs cleaner, and toxic chemicals faster than ever before.

The following articles are the most accessed digital object identifier (DOI) manuscripts for Spectroscopy and LCGC International during the month of August 2026. Ten articles are individually ranked here by DOI page views.

The bulky bench-top NIR spectrometer is quietly being dismantled and rebuilt as a wafer-scale photonic chip, a self-calibrating algorithm, and a sensor small enough to ride in a shirt pocket. What once demanded a grating, a moving mirror, and a climate-controlled lab now fits inside a handheld module, a bioreactor probe, or a drone payload, and it increasingly figures out what it is looking at on its own.

Reliability, dynamic measurements, artificial intelligence, and real-world applications are reshaping Raman spectroscopy – while Molecular Photonics points toward new translational frontiers.