How Using Raman Spectroscopy and SIMPLISMA Can Accelerate the Study of Polymorphs: A Case Study Using Carbamazepine (PDF)

June 2, 2004
Andrey Bogomolov

,
Michel R.J. Hachey

,
Keith C. Gordon

,
Thomas Rades

Special Issues

Special Issues, Special Issues-06-02-2004, Volume 0, Issue 0

The authors show how a multivariate curve resolution algorithm, called SIMPLe-to-use Interactive Self-modeling Mixture Analysis (SIMPLISMA), can facilitate the quantitative and qualitative analysis of difficult samples, and apply the algorithm to a technically challenging Raman spectra series for carbamazepine polymorphs.