How Using Raman Spectroscopy and SIMPLISMA Can Accelerate the Study of Polymorphs: A Case Study Using Carbamazepine (PDF)
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The authors show how a multivariate curve resolution algorithm, called SIMPLe-to-use Interactive Self-modeling Mixture Analysis (SIMPLISMA), can facilitate the quantitative and qualitative analysis of difficult samples, and apply the algorithm to a technically challenging Raman spectra series for carbamazepine polymorphs.
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