Surface Plasmon Resonance imaging (SPRi) instruments enable a large number of different label-free molecular interactions to be monitored simultaneously and in parallel in a single experiment. This multiplexing capability will be demonstrated using an antibody SPRi-Biochip™.
Microspectroscopy, the marriage of spectroscopic chemical identification with microscopic spatial resolution, has advanced from Perkin-Elmer's first commercial infrared microspectrometer in 1953 to today's nanoscale AFM-IR probes, synchrotron-brightness infrared beamlines, and compact hyperspectral tissue imaging devices being developed for AI-assisted cancer detection.
Atomic spectroscopy has quietly gone from counting elements in bulk to counting single nanoparticles, imaging tissue at the micrometer scale, and reading Martian rocks from several meters away. The instruments got smaller, the software got smarter, and the questions they can now answer got a lot more interesting.