Articles by HORIBA Scientific

***Live: Tuesday, November 24, 2020 at 11am EST | 8am PST | 4pm GMT | 5pm CET ***
Join us for this webcast on surface enhanced Raman scattering (SERS) applications in the biomedical field. Learn how biofunctionalized metal nanoparticles can act as bright nanosensors, providing diagnostic information on biosystems, selectively targeting cancer cells and probing pH with very high spatial resolution.
*** On demand available after final airing until Nov. 24, 2021.***

This HORIBA application note demonstrates the importance of an intermediate slit and the critical role it plays in stray light rejection of a true double monochromator

*** Live: Tuesday, Oct. 27, 2020 at 11am EDT| 8am PDT| 3pm GMT| 4pm CET*** How would you connect the ocean, a crime scene and prehistoric sites? You could do it by using micro-Raman (also called Raman microscopy) spectroscopy! Join us for this web seminar to learn about the versatility and different modalities of micro-Raman Spectroscopy. Then, discover how the micro-Raman can be used in a wide range of applications to solve analytical challenges. ***On demand available after final airing until Oct. 27, 2021***

Characterizing Raman spectra of modified celluloses in pharmaceuticals, food, and materials industries. Raman spectra are compared and analyzed to determine spectroscopic features that can be useful in determination of physical and chemical properties.

Photoluminescence (PL) lifetime measurements in NIR are the key parameters in assessing the optical efficiency of devices involving lanthanides, as well as in quality control during their manufacturing.

Don’t miss this opportunity to learn about how Raman spectroscopy can be added to your particle characterization methods for chemical identification/characterization. See real life examples where automated particle-Raman characterization has provided a fast and actionable solution to manufacturing problems and added insight into formulation research.

Optimization and follow up of manufacturing process of plastics films are easily achieved using Pulsed RF Glow Discharge Optical Emission Spectrometry. This technique allows the fast detection of defects and presence of contaminants.

Combining SPRi technology with MALDI mass spectrometry on the same surface is a powerful approach for the analysis of biomolecular interactions, allowing measurement of biomolecular interactions by SPRi, and then detection of the retained ligands by MALDI mass spectrometry directly from the sensor surface.

This appnote shows the benefits of using pulsed RF GDOES for the analysis of films containing nanoparticles

This appnote shows the application of GDOES to materials used in Solid Oxide Fuel Cells, which are based on chemical oxidation of the fuel rather than its combustion, offering high efficiency without forming air pollutants.

Raman spectroscopy has been used to analyze the process of micro-encapsulation of flavors. This contribution shows the example of distribution of limonene and quantification of its content within the micro-particles.

During the charging and discharging process, lithium ions travel from one electrode to another. This application note explains how Raman Spectroscopy can be helpful in the analysis of cathodes and anodes for R&D and QC.

Surface Plasmon Resonance (SPR) is an optical technique that offers label-free biomolecular analyses, providing information on kinetic processes (association and dissociation), binding affinity, analyte concentration and real time molecule detection. It has become a powerful tool for the analysis of biomolecular events involved in drug development, cancer research, and antibody screening

Exposure to warm/humid conditions may cause pharmaceutical formulations to undergo change in hydration level, affecting properties and/or efficiency of the drug. Raman spectroscopy, with a temperature and humidity controller can mimic harsh conditions, monitor properties of ingredients and track modifications induced by environmental changes.

Time‐resolved Fluorescence can analyze potential health benefits from antioxidant activity of curcumin, found in turmeric. Curcuminoids, weakly fluorescent in aqueous solution, show quantum yield increases upon interaction with a protein, such as human serum albumin.

Locate particles, generate size/shape statistics, select particles based on size/shape, and acquire Raman spectra. Easily locate and identify particulate matter, including pharmaceutical materials, trace forensic evidence, geological rock/mineral particles, and airborne contaminants trapped on filters

The application note explains how the Raman Spectroscopy can be helpful in the analysis of cathodes and anodes in Li-ion batteries.

Statistical and morphological analysis of particles on a filter has been complemented by chemical analysis based on Raman spectroscopy using the ParticleFinder tool, allowing further insight into the particle composition and its origin within a production line.

Direct Identification of Clinically Relevant Microorganisms on Solid Culture Media by Raman Spectroscopy
ByEunah Lee,HORIBA Scientific,R. Mathey,P. Joly,F. Pinston,O. Gal,I. Espagnona,A. Novelli-Rousseau,M. Dupoy,D. Ostrovskii,D. Leroux,F. Mallard Evaluation of the discrimination power of Raman spectroscopy in decreasing turnaround time in clinical diagnosis, when analyzing microcolonies from nine bacterial and one yeast species directly on solid culture medium after a shortened incubation time.

LabSpec 6 MultiWell module and HORIBA Raman systems enable non-destructive analysis with high throughput screening using arrayed sampling devices, automated sample movement, autofocus devices, and automated data acquisition to acquire spectra from hundreds of samples sequentially.

OLED technology offers advantages to LCD technology: efficiency, high display quality, high contrast rate, lower energy consumption, etc. Ellipsometry, a non-destructive and sensitive optical technique, can provide information on performance improvements of these devices.

Peak emission for silicon occurs at values beyond the range of sensitivity for silicon-based detectors, like CCDs. EMCCDs combine a larger field of view and higher resolution with high sensitivity in the NIR at lower cost.

Locate particles, generate size/shape statistics, select particles based on size/shape, and acquire Raman spectra. Easily locate and identify particulate matter, including pharmaceutical materials, trace forensic evidence, geological rock/mineral particles, and airborne contaminants trapped on filters

Time‐resolved Fluorescence can analyze potential health benefits from antioxidant activity of curcumin, found in turmeric. Curcuminoids, weakly fluorescent in aqueous solution, show quantum yield increases upon interaction with a protein, such as human serum albumin.

An SPR experiment is composed of several steps, from ligands immobilization to data analysis. Results can be reached using a SPRi system for real time and label-free, specific and sensitive interactions.

Surface Plasmon Resonance imaging (SPRi) instruments enable a large number of different label-free molecular interactions to be monitored simultaneously and in parallel in a single experiment. This multiplexing capability will be demonstrated using an antibody SPRi-Biochip™.

Taking advantage of the multiplexing capabilities of SPR imaging, combined
with the flexibility of the SPRi-Arrayer can help speed up the optimization steps necessary prior to kinetics analysis.

ParticleFinder: Locate particles, generate size/shape statistics, select particles based on size/shape, and acquire Raman spectra. Easily locate and identify particulate matter, including pharmaceutical materials, trace forensic evidence, geological rock/mineral particles, and airborne contaminants trapped on filters.