Real-Time Protein Monitoring: The Power of UV-VIS and Raman Spectroscopy in Bioprocessing



Webinar Date/Time: Thu, Nov 30, 2023 11:00 AM EST

Get your daily mental creatine with this beefcake presentation on monitoring proteins in bioreactor settings using a combination of UV-VIS and Raman spectroscopy. Learn the benefits and hurdles of each approach, plus the processing techniques to give you gains.

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Event Overview:

Monitoring protein concentration is an essential part of any bioprocess, and as new techniques are developed, there are more avenues and options to track this in real-time. Conventional UV-VIS spectroscopy is the most common method of protein monitoring and analysis, but as Raman spectroscopy becomes more affordable and democratized, it offers another perspective of the same analytes. This talk will investigate the benefits and limitations of both UV-VIS and Raman spectroscopy approaches to tracking protein in a bioreactor setting, including considerations around technical implementation, cost effectiveness, and post-processing techniques.

Key Learning Objectives:

  • Understand the differences between UV-VIS and Raman spectroscopy to monitor proteins
  • Learn where the largest technical hurdles exist in real-world implementation
  • Discover broadband processing techniques to deconvolute and pull-out relevant information

Who Should Attend:

  • Anyone working with bioprocesses or pharmaceutical manufacturing
  • Researchers looking to marry traditionally-separated methodologies


Derek Guenther
Senior Product Scientist
Ocean Optics

Derek A. Guenther has a B.S. in Chemical Engineering from the University of South Florida with a minor in Inorganic Chemistry. His work at the USF Institute for Environmental Studies focused on development of novel silica-based algaecides targeting invasive species in Florida fresh waterways. His strengths and passions lie in new chemical sensor developments and spectral numerical processing. Derek has spent over 15 years at Ocean Optics developing and supporting the oxygen, pH, and SERS-based optical sensor products, and also performing years of customer feasibility studies with the Lab Services Team. Today he works with the strategic marketing team to broadcast the excitement of spectroscopy out into the world.

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