Spectroscopy E-Books
Effluents from wastewater treatment plants (WWTPs) are a major source of contamination by pharmaceuticals and personal care products (PPCPs) in the environment. The presence of low levels of PPCPs in surface and drinking water sources raises public concern because of the potential detrimental ecological effects of these contaminants. Because of these concerns, scientists and engineers have been interested in detecting PPCPs in water to evaluate their fate and transport in the environment, as well as monitor their transformation and degradation at WWTPs. Liquid chromatography coupled with mass spectrometry (LC–MS) has been the method of choice for separation and detection of PPCPs, because PPCPs are highly soluble in water and have low volatility. The majority of LC–MS methods use electrospray ionization either in positive or negative mode, with an acidic or basic mobile phase, respectively. As an alternative, this article presents the use of “wrong-way-round ionization” in electrospray mass spectrometry, where protonation of neutral or weakly basic molecules occurs in a strongly basic mobile phase in LC–MS. When “wrong-way-round ionization” was employed in LC–MS for the analysis of PPCPs in wastewater samples, increased signal intensities, by at least an order of magnitude, were observed in PPCPs with diverse polarity and acidic properties.
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An Interview with AES Mid-Career Award Recipient Jason Dwyer
July 25th 2024Jason Dwyer of the University of Rhode Island has been named the recipient of the American Electrophoresis Society’s Mid-Career Award, which honors exceptional contributions to the field of electrophoresis, microfluidics, and related areas by an individual who is currently in the middle of their career.
Glucose's Impact on Brain Cancer Cells Unveiled Through Raman Imaging
July 25th 2024Researchers have used Raman spectroscopy and chemometric methods to reveal how glucose affects normal and cancerous brain cell metabolism. Their findings highlight specific biomarkers that can distinguish metabolic changes, potentially aiding in cancer research and treatment.