ADME/Tox Profiling Using Coulometric Electrochemistry and Electrospray Ionization Mass Spectrometry (PDF)

Smith,Ray;Acworth,Ian;Waraska,John;Gamache,Paul;McCarthy,Ryan;

Article

Spectroscopy

June 1, 2003

Spectroscopy

Spectroscopy-06-01-2003

Volume

ADME/Tox Profiling Using Coulometric Electrochemistry and Electrospray Ionization Mass Spectrometry (PDF)

Author(s):

Ray Smith,Ian Acworth

The authors discuss the use of serial coulometric flow cells coupled online with electrospray ionization mass spectrometry in predictive assays for absorption, distribution, metabolism, excretion, toxicity (ADME/Tox), and stability implemented at early stages of drug discovery.

To view a PDF of this article from the Spectroscopy Online archives, click this link.

Articles in this issue

End of the Spectrum: The School of Drug Discovery ? Oregon Health and Science University Develops a Chemical Biology Program (PDF)

Challenges in the Interpretation of Data from Hyphenated Techniques, Part I: General Principles (PDF)

Improving Ionization in Mass Spectrometry (PDF)

ADME/Tox Profiling Using Coulometric Electrochemistry and Electrospray Ionization Mass Spectrometry (PDF)

Get essential updates on the latest spectroscopy technologies, regulatory standards, and best practices—subscribe today to Spectroscopy.

Subscribe Now!

ADME/Tox Profiling Using Coulometric Electrochemistry and Electrospray Ionization Mass Spectrometry (PDF)

Newsletter