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Special Issues

Spectroscopy Supplements

Special Issues-05-02-2004
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TLC-MALDI in Pharmaceutical Analysis (PDF)

Thin-layer chromatography (TLC) is a widely used technique for the rapid examination of compound purity. The amount of qualitative information, however, is limited to the retention factor of compounds. The technique described here enables the direct determination of TLC plates by MALDI MS.

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Robert Ewing of the Pacific Northwest National Laboratory. | Photo Credit: Will Wetzel
Robert Ewing of the Pacific Northwest National Laboratory. | Photo Credit: Will Wetzel