This book makes serious efforts to include examples of the various ways in which information about the underlying behavior of a system can be extracted from data obtained from the system.
AI and Dual-Sensor Spectroscopy Supercharge Antibiotic Fermentation
June 30th 2025Researchers from Chinese universities have developed an AI-powered platform that combines near-infrared (NIR) and Raman spectroscopy for real-time monitoring and control of antibiotic production, boosting efficiency by over 30%.
Toward a Generalizable Model of Diffuse Reflectance in Particulate Systems
June 30th 2025This tutorial examines the modeling of diffuse reflectance (DR) in complex particulate samples, such as powders and granular solids. Traditional theoretical frameworks like empirical absorbance, Kubelka-Munk, radiative transfer theory (RTT), and the Hapke model are presented in standard and matrix notation where applicable. Their advantages and limitations are highlighted, particularly for heterogeneous particle size distributions and real-world variations in the optical properties of particulate samples. Hybrid and emerging computational strategies, including Monte Carlo methods, full-wave numerical solvers, and machine learning (ML) models, are evaluated for their potential to produce more generalizable prediction models.
Combining AI and NIR Spectroscopy to Predict Resistant Starch (RS) Content in Rice
June 24th 2025A new study published in the journal Food Chemistry by lead authors Qian Zhao and Jun Huang from Zhejiang University of Science and Technology unveil a new data-driven framework for predicting resistant starch content in rice
New Spectroscopy Methods Target Counterfeit Oral Medication Syrups
June 23rd 2025Researchers at Georgia College and Purdue University have developed a fast, low-cost method using Raman and UV–visible spectroscopy combined with chemometric modeling to accurately screen and quantify active ingredients in over-the-counter oral syrups, helping to fight counterfeit medications.
Short Tutorial: Complex-Valued Chemometrics for Composition Analysis
June 16th 2025In this tutorial, Thomas G. Mayerhöfer and Jürgen Popp introduce complex-valued chemometrics as a more physically grounded alternative to traditional intensity-based spectroscopy measurement methods. By incorporating both the real and imaginary parts of the complex refractive index of a sample, this approach preserves phase information and improves linearity with sample analyte concentration. The result is more robust and interpretable multivariate models, especially in systems affected by nonlinear effects or strong solvent and analyte interactions.