IMS for Cleaning Verification (PDF)

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Special Issues

Spectroscopy Supplements, Special Issues-01-02-2005, Volume 0, Issue 0

The need to verify cleaning between manufacturing runs presents a special challenge to the analytical chemist. In this article, the principles of ion mobility spectrometry are described, its performance is compared to HPLC for the analysis of cleaning validation samples, and findings are presented from a study to establish the feasibility of using IMS in validating a cleaning verification method.