Special Issues
This article reviews the development of FDA's PAT Initiative along with CPAC's ANSI/ISA-76.00.02 (2002) (NeSSI) development. The intent is to show how the NeSSI components could contribute to the PAT philosophy and physical requirements.
High-Speed Laser MS for Precise, Prep-Free Environmental Particle Tracking
April 21st 2025Scientists at Oak Ridge National Laboratory have demonstrated that a fast, laser-based mass spectrometry method—LA-ICP-TOF-MS—can accurately detect and identify airborne environmental particles, including toxic metal particles like ruthenium, without the need for complex sample preparation. The work offers a breakthrough in rapid, high-resolution analysis of environmental pollutants.