TLC-MALDI in Pharmaceutical Analysis (PDF)

April 29, 2004
Don S. Richards

Malcolm R. Clench

Anna Crecelius

Special Issues

Special Issues, Special Issues-05-02-2004, Volume 0, Issue 0

Thin-layer chromatography (TLC) is a widely used technique for the rapid examination of compound purity. The amount of qualitative information, however, is limited to the retention factor of compounds. The technique described here enables the direct determination of TLC plates by MALDI MS.