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Bioreactor Fermentation Monitoring with Raman Spectroscopy
February 1st 2020Raman spectroscopy’s high analytical selectivity and insensitivity to water is well suited for process monitoring in biotechnology. Here we explore the fermentation of glucose, a common feedstock, with a commonly used microorganism, yeast. Applying multivariate tools, we can monitor the main reactants and products with high sensitivity: glucose, ethanol, and carbon dioxide.
QTRam for Content Uniformity Analysis of Low-Dose Pharmaceutical Tablets
February 1st 2020Compressed tablet is the most common form of orally administered drug. The United States Pharmacopeia (USP) chapter <905> requires that dosage uniformity of such products containing less than 25 mg or less than 25% active pharmaceutical ingredients (API) by weight must be analyzed for content uniformity, which is based on the assay of each API in a number of individual dosage units.
Tracking Photocuring via ATR-FT-IR with Illumination through the ATR Element
February 1st 2020The utility of the GladiATR diamond ATR, modified with an internal liquid light guide to illuminate the sample from underneath the ATR element, was explored to analyze the photo-polymerization of carbitol acrylate at 405 nm using 1 wt% TPO.
Gallium Nitride Quality and Stress Field Characterization with 3D Confocal Raman Imaging
February 1st 2020The quality and stress field properties of gallium nitride (GaN) crystals must be investigated in order to refine production processes. 3D Confocal Raman microscopy is uniquely capable of the chemical c and visualizing strain in this material.
A Robust, High Performance, Fully Demountable ICP Torch
January 28th 2020Examine the benefits of Glass Expansion’s robust, high performance, fully demountable patented D-Torch. The D-Torch uses high precision engineering to provide the benefits of lower running costs, chemical inertness and configurable injector geometry, without compromising usability, performance or durability. www.geicp.com/D-Torch
Monitoring the Fate of Silver Nanoparticles in Seawater Using Single Particle ICP-MS
January 22nd 2020This work demonstrates the ability of the NexION® ICP-MS, coupled to the dedicated Syngistix™ Nano Application software module, to measure silver (Ag) nanoparticles in seawater and track their transformations over time.
EPA Method 8015C for Diesel Range Organics
January 22nd 2020EPA 8015C is a gas chromatographic method used to establish concentrations of a variety of non-halogenated volatile organic compounds, semivolatile organic compounds, and petroleum hydrocarbons. For the purpose of this application, a Clarus® 690 GC was used for the analysis of petroleum hydrocarbons, specifically Diesel Range Organics (DRO).