Angela Flack

As an alternative drug delivery route, transdermal patches control the amount of medication a patient receives. With confocal Raman microscopy it is possible to create a Raman 3D map and thus visualize and analyze the layers of a transdermal patch without damaging it, allowing for quality control and stability measurements.

In this application note, we investigate the phase transitions occurring in polyethylene and nylon-6 using the Edinburgh Instruments RMS1000 Raman Microscope and a temperature stage.