Author | Douglas W. Later

Articles

Rapid Chemical Threat Identification by SPME-GC–TMS

April 01, 2010

Special Issues

Article

A person-portable gas chromatography–mass spectrometry (GC–MS) system employing a toroidal ion trap mass spectrometry (TMS) detector was used to analyze chemical threat related compounds. Introduction of analytes into the heated injector of the instrument was by solid-phase microextraction (SPME), and fast resistive heating of a low thermal mass (LTM) gas chromatography column assembly provided rapid analysis times. Methodology for positive identification of chemical threats can combine chromatographic retention time, comparison to traditional electron ionization mass spectral libraries, and observation of expected pseudomolecular ions produced through self-chemical ionization. Methods are discussed for sampling by SPME with GC–MS analysis in the field to measure airborne analyte concentrations.

Rapid Field Detection of Chemical Warfare Agents and Toxic Industrial Chemicals Using a Hand-Portable GC–TMS System

April 01, 2009

Special Issues

Article

In this article, methods developed for rapid, automated detection of CWAs and TICs using a low thermal mass capillary gas chromatograph coupled to a toroidal ion trap mass spectrometer (TMS) are presented.