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QTRam for Content Uniformity Analysis of Low-Dose Pharmaceutical Tablets

QTRam for Content Uniformity Analysis of Low-Dose Pharmaceutical Tablets

Jun Zhao;Christopher Kautz;Andrés Román;B&W Tek, LLC;Rutgers, the State University of New Jersey
February 1st 2020

Compressed tablet is the most common form of orally administered drug. The United States Pharmacopeia (USP) chapter <905> requires that dosage uniformity of such products containing less than 25 mg or less than 25% active pharmaceutical ingredients (API) by weight must be analyzed for content uniformity, which is based on the assay of each API in a number of individual dosage units.

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