Advancing the Use of NIR Spectroscopy in Combination with Clinical MRI
Engineers from the Thayer School of Engineering at Dartmouth (Hanover, New Hampshire) and radiologists are developing new approaches for an emerging technique in diagnostic imaging for breast cancer-MRI with near ?infrared spectroscopy (IIRS) as reported in the February issue of the journal Academic Radiology.
Engineers from the Thayer School of Engineering at Dartmouth (Hanover, New Hampshire) and radiologists are developing new approaches for an emerging technique in diagnostic imaging for breast cancer-MRI with near –infrared spectroscopy (IIRS) as reported in the February issue of the journal Academic Radiology.
Combined MRI¬–NIRS may benefit women whose mammograms showed an abnormality and require further testing to rule out cancer. The test would be conducted before an invasive biopsy to look for tumors. For the new method to work successfully in routine patient care, MRI–NIRS must adapt to an individual’s body size as well as accommodate a range of cup sizes. The equipment must also mobilize and maintain contact with the breast.
MRI–NIRS testing may offer specific advantages to women with dense breasts, who are more likely to develop and die from breast cancer. A dense breast is harder for a radiologist to “see through” when using traditional imaging equipment, which reportedly lacks the sensitivity to penetrate the dense tissue. Standard breast screening is effective 77-97 percent of the time in a normal breast, but precision falls to 63-89 percent when a breast is dense.
Getting accurate IR spectra on monolayer of molecules
April 18th 2024Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.
Achieving Accurate IR Spectra On Monolayer of Molecules
April 18th 2024Creating uniform and repeatable monolayers is incredibly important for both scientific pursuits as well as the manufacturing of products in semiconductor, biotechnology, and. other industries. However, measuring monolayers and functionalized surfaces directly is. difficult, and many rely on a variety of characterization techniques that when used together can provide some degree of confidence. By combining non-contact atomic force microscopy (AFM) and IR spectroscopy, IR PiFM provides sensitive and accurate analysis of sub-monolayer of molecules without the concern of tip-sample cross contamination. Dr. Sung Park, Molecular Vista, joined Spectroscopy to provide insights on how IR PiFM can acquire IR signature of monolayer films due to its unique implementation.
