Appendix XI: UV–vis

May 1, 2014

Appendix XI: UV–vis

Manufacturer: Agilent Technologies

Product name: Cary 8454

UV–vis diode-array spectrophotometer

New this year: Photodiode array (PDA) technology, the successor to the Agilent 8453 UV-Vis

Used for: Lab process, handheld analysis

Special Features: Pre-aligned light sources, hard-surface buttons, cell holders (standard, thermostatted, long-path), cell transport, sipper, autosamplers, pre-aligned lamps, single audit trail, supports electronic records and passwords, no moving parts

Software: 21CFR11 compliant, may be used in other equipment

Suggested applications: Routine applications QA/QC pharma, kinetics.

Primary benefits: complete spectrum with every measurement, from 190 to 1100 nm., simultaneous multiwavelength measurement, component analysis and tablet dissolution.

Unique features: UV–vis spectrum in less than 1 s.

Manufacturer: Agilent Technologies

Product name: Cary 7000

Universal measurement UV–vis spectrometer

New this year: Complete sample characterization in a single sequence without moving the sample

Used for: Lab, process, handheld analysis

Measurement modes: Specular reflectance, diffuse reflectance, diffuse scattering, glossy scattering, scattered transmission, direct transmission

Accessory/component: Solids autosampler

Special features: Complete sample characterization, absolute reflection and transmission, diffusely scattered transmission and reflection, huge sample chamber, control beam collimation, simple method set up, 10 Abs range, multi-angle, absolute reflection (R), transmission (T), absorbance (A) and scattering measurements

Software: Available as separate product, may be used in other equipment

Suggested applications: Research, development and QA/QC in optics, thin films/coatings, solar and glass, challenging samples such as high optical density filters.

Unique features: Measure absolute reflection and transmission at variable angles, 10 Abs range, direct-view detection system

Manufacturer: Areo Creative Corp.

Product name: Mini Spectral Sensors

UV–vis

Used for: Process, handheld

Dimensions: 25 x 25 x 5 mm

Weight: 10–12 g

Measurement mode: Transmission, reflection, excitation

Special features: Sensor modules with smallest size/volume, but function as mini spectrometers; available as separate product, may be used in other equipment.

Suggested applications: Biological science, medical and health care, pharmaceutical, agriculture, food/beverage industry, chemistry, material science, homeland security, military and defense, environment science, color sensing

Unique features: Capability of accurate spectral measurements, high efficiency in detecting input light signals, light weight with compact sizes and volumes, easy integration with mobile devices and handheld units

Manufacturer: Distek, Inc.

Product name: Opt-Diss 405™

UV–vis spectrometer dissolution tester

Used for: Lab, process analysis

Accessory/component: Integral probe for dissolution testing

Software: Available as separate product, 21CFR11 compliant, cGMP compliant, compatible with other manufacturers' equipment

Suggested applications: In situ dissolution testing

Manufacturer: Drop Technology

Product name: TLDA Microvolume Spectrophotometer

Microvolume (sample size = 1–4 µL) UV–vis spectrometer

New this year: Instrument based on Drop Science technology

Used for: Lab analysis

Dimensions: 454 × 250 × 330 mm (D × W × H)

Weight: 11 kg

Measurement mode: Drop Science technology

Specialty accessory description: Wavelength range 200–750 nm. Technology used is unlike other microvolume instruments. The drop under test sits on a quartz plinth, without any disturbance, while the measurement is being made. Removal after measurement is simple: just wipe the sample from the quartz. Is also available stand-alone (see Accessories).

Special features: Only a small sample volume (1-4 µL) is required. Can be used where larger volumes and dilution may be required. Very fast (milliseconds) measurement. Pulsed xenon light source (no lamp needing regular replacement). Good for high-value samples.

Software: Available as separate product, cGMP compliant

Suggested applications: dsDNA, ssDNA, RNA, protein quantification

Primary benefits: Ease of use, lack of cross contamination from one sample to another and the ability to calibrate the instrument using NIST traceable standards. Because of our technology, accuracy and reproducibility can be achieved in all application areas.

Unique features: Sample loading and removal for either right or left handed operation. Quick and simple sample chamber opening and closing.

Manufacturer: Ocean Optics, Inc.

Product name: STS-UV

UV–vis spectrometer

New this year: UV spectral analysis

Used for: Lab, process, handheld applications

Dimensions: 40 x 42 x 24 mm; weight: 60 g

Measurement mode: Absorption, transmission

Special features: Wavelength range = 190-650 nm, S/N > 1500:1, Dynamic range= 4600:1

Software: Available as separate product, may be used in other equipment, compatible with other manufacturers' equipment.

Suggested applications: Quality control, remote sensing, low-concentration absorbance measurements, high intensity laser characterization, point of care diagnostics, emission spectroscopy

Primary benefits: Optical resolution, sensitivity and stability comparable to much larger, more expensive spectrometers.

Manufacturer: SciAps, Inc.

Product name: Navigator

UV–vis–IR spectrometer

New this year: Portable broadband absorption spectrometer. Wide spectral range from 350 nm to 2500 nm captures signature absorption patterns spanning from UV through NIR. This allows for a wider variety of minerals and compounds to be identified and is compatible with TSG and SpecMIN for field geologists.

Used for: Handheld/portable applications

Dimensions: 14.5 x 13.5 x 7.5 in.

Weight: 17.95 lb (8.14 kg)

Suggested applications: Mineral exploration, phamaceuticals, food safety, university, field geology and chemistry programs, plastics recycling and quality, general products quality

Primary benefits: Portable, field hardened absorption spectrometer spectral range from 350nm to 2500 nm, capturing signature absorption patterns spanning the UV through the NIR, data from multiple instruments are easily uploaded for comparison and logging.

Unique features: Broad spectral range from 350 nm to 2500 nm, robust spectrometer designed for water, dust and shock resistance, meeting IP 54 standards; pistol-grip probe holds any smartphone or tablet Java software engine for exceptional compatibility for exporting data. Instant connectivity to the cloud via wireless and broadband, compatible with TSG and SpecMIN for field geologists, compatible with common off-the-shelf chemometrics programs like Camo Unscrambler.

Manufacturer: SpectroClick Inc.

Product name: AAH-200

UV–vis spectrometer

New this year: The company's first product is a portable visible absorption spectrometer.

Used for: Handheld/portable analysis

Dimensions: 9 cm × 9 cm × 3.5 cm

Weight: 0.5 kg

Measurement mode: Transmission

Special features: Portable, USB-powered, unique, patent-pending grating arrangement that exploits high pixel count, eight-bit per color cameras to do spectrometry with three order of magnitude dynamic range.

Software: Proprietary software required; may be used in other equipment.

Suggested applications: Education, sample screening and triage, back-country analysis.

Primary benefits: Self-contained. Runs on power from a USB port.

Unique features: Uses self-calibrating software to compensate for limitations of low-cost hardware.

Manufacturer: StellarNet Inc.

Product name: SILVER-Nova

UV–vis spectrometer

New this year: New high performance spectrometer; ruggedized enclosure with a fiber-optic input for the 190-1110 nm wavelengths

Used for: Lab, process, handheld applications

Measurement modes: Absorbance, transmission, reflectance, radiometric

Special features: High sensitivity, TE cooled, widest range, rugged

Software: Available as separate product, may be used in other equipment, compatible with other manufacturers' equipment.

Suggested applications: Wide-range UV–vis–NIR spectroscopy

Primary benefits: High sensitivity and wide range (190-1110 nm)