This study demonstrates how to measure ultratrace (parts-per-trillion) levels of inorganic impurities in isopropyl alcohol, a key process chemical for semiconductor fabrication. The method includes online calibration using the IAS Automated Standard Addition System for an Agilent ICP-QQQ instrument. The method allows the accurate and reliable quantification of ultratrace level impurities in IPA without requiring a highly skilled analyst.
Enhancing Trace Element Analysis with Inductively Coupled Plasma Mass Spectrometry
May 15th 2025Elemental analysis is crucial in a wide variety of applications from detecting toxic elements within the environment, to ensuring drinking water is safe for human consumption, to food product safety. ICP-MS—able to measure an atom’s mass—offers low detection limits in the range of parts per trillion (ppt), making it a widely used method that can detect toxic elements well below regulatory limits. This paper expands upon how new ICP-MS technology can meet the challenges associated with heightened demands for element analysis and the hurdles laboratories face when analyzing high-matrix samples.